106232
Trifluoroacetic anhydride
ReagentPlus®, ≥99%
Synonym(s):
TFAA
Sign Into View Organizational & Contract Pricing
All Photos(3)
About This Item
Linear Formula:
(CF3CO)2O
CAS Number:
Molecular Weight:
210.03
Beilstein:
746197
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
Recommended Products
vapor pressure
6.28 psi ( 20 °C)
Quality Level
100
200
product line
ReagentPlus®
Assay
≥99%
refractive index
n20/D 1.3 (lit.)
bp
39.5-40 °C (lit.)
mp
−65 °C (lit.)
density
1.511 g/mL at 20 °C (lit.)
SMILES string
FC(F)(F)C(=O)OC(=O)C(F)(F)F
InChI
1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10
InChI key
QAEDZJGFFMLHHQ-UHFFFAOYSA-N
Looking for similar products? Visit Product Comparison Guide
Application
For the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for GC analysis. Also used in the oxidation of aldehydes to acids, esters, or amides. Trifluoroacetic anhydride can undergo reaction with deoxyguanosine in pyridine to give the corresponding 6-substituted-2′-deoxyguanosine derivatives. It can also react with urea-hydrogen peroxide complex to generate peroxytrifluoroacetic acid, which can convert aldoximes to nitroalkanes.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Supplementary Hazards
Storage Class Code
8B - Non-combustible corrosive hazardous materials
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Albert W Xiao et al.
Nature materials, 19(6), 644-654 (2020-02-26)
The application of transition metal fluorides as energy-dense cathode materials for lithium ion batteries has been hindered by inadequate understanding of their electrochemical capabilities and limitations. Here, we present an ideal system for mechanistic study through the colloidal synthesis of
"Synthesis of 6-substituted 2'-deoxyguanosine derivatives using trifluoroacetic anhydride in pyridine"
Fathi R, et al.
Tetrahedron Letters, 31(03), 319-321 (1990)
"Synthesis of functionalized nitroalkanes by oxidation of oximes with urea-hydrogen peroxide complex and trifluoroacetic anhydride"
Ballini R, et al.
Tetrahedron Letters, 33(33), 4835- 4838 (1992)
Tetrahedron Letters, 27, 3995-3995 (1986)
Angelos Halaris et al.
Journal of psychiatric research, 66-67, 118-126 (2015-05-27)
A pro-inflammatory state and a dysregulation in the tryptophan/kynurenine pathway have been documented in depression. This study examined whether treatment with the SSRI, escitalopram (ESC), could suppress inflammation and favorably shift metabolites of the kynurenine pathway in patients with major
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service