Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

114529

Sigma-Aldrich

Phenol Red

ACS reagent

Synonym(s):

Phenolsulfonphthalein

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C19H14O5S
CAS Number:
143-74-8
Molecular Weight:
354.38
Beilstein:
326470
EC Number:
205-609-7
MDL number:
MFCD00003552
UNSPSC Code:
12171500
PubChem Substance ID:
24847179
NACRES:
NA.47

grade

ACS reagent

Quality Level

200

form

powder

clarity of soln

passes test

technique(s)

titration: suitable

visual transition interval

6.8-8.2, yellow to red

solubility

water: 0.77 g/L at 100 °C

λmax

360 nm
557 nm (2nd)

ε (extinction coefficient)

≥10000 at 288-294 nm in H2O
≥55000 at 555-561 nm in H2O
≥7000 at 357-363 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc(cc1)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)cc4

InChI

1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H

InChI key

BELBBZDIHDAJOR-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Phenol Red is a phenolsulfonphthalein compound. It is present as a sulfonated hydroxyquinone in weakly acidic aqueous solutions. In alkaline solutions, the dye forms a hydrophilic dianion (a small, red anion that has a larger conjugated system than the yellow hydroxyquinone).

Application

Phenol red is commonly used as a pH indicator in biology and medicine. It is incorporated into microbiological culture media for the identification of Escherichia coli strains. Its clinical diagnostic applications include the investigation of gastric and duodenal ulcers and the assessment of tear function in ophthalmology. Phenol red is also used as a tracer to assess the permeability of the ileal mucosal membrane and to assess bacterial leakage through root-filling materials in dentistry.
Phenol Red has been used for the preparation of phenol red gavage meal for measurement of gastric emptying in rats.
Suitable for use as a pH indicator.

Biochem/physiol Actions

Phenol Red is a pH indicator which changes color from yellow to red.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H335

Hazard Classifications

Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000401210
0000401211
0000389289
0000389290
0000372792

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Preclinical gastrointestinal prokinetic efficacy and endocrine effects of the ghrelin mimetic RM-131.
Van der Ploeg L, et al.
Life Sciences, 109, 20-29 (2014)
TiO2 nanotube arrays of 1000 ?m length by anodization of titanium foil: phenol red diffusion.
Paulose M, et al.
The Journal of Physical Chemistry C, 111, 14992-14997 (2007)
Shin-Nosuke Uno et al.
Nature chemistry, 6(8), 681-689 (2014-07-24)
Single-molecule localization microscopy is used to construct super-resolution images, but generally requires prior intense laser irradiation and in some cases additives, such as thiols, to induce on-off switching of fluorophores. These requirements limit the potential applications of this methodology. Here
Sabine C Den Hartogh et al.
Stem cells (Dayton, Ohio), 33(1), 56-67 (2014-09-05)
Understanding early differentiation events leading to cardiogenesis is crucial for controlling fate of human pluripotent stem cells and developing protocols that yield sufficient cell numbers for use in regenerative medicine and drug screening. Here, we develop a new tool to
Tatsuya Murakami et al.
ACS nano, 8(7), 7370-7376 (2014-06-20)
Surface engineering of mesoscopic metal nanoparticles to increase biocompatibility and cell interaction is important for improvement of their therapeutic properties. Here, we describe a strategy to stabilize mesoscopic metal nanoparticles and to enhance their cell interaction by stepwise addition of
View All Related Papers

Protocols

Hand-casting gels for PAGE and SDS-PAGE using mPAGE® TurboMix Bis-Tris Gel Casting Kits

Simplify your SDS-PAGE gel preparation with our pre-mixed solutions and protocols to achieve precise protein separation.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service