456756
Iodomethane solution
2.0 M in tert-butyl methyl ether, contains copper as stabilizer
Synonym(s):
Methyl iodide
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About This Item
Empirical Formula (Hill Notation):
CH3I
CAS Number:
Molecular Weight:
141.94
Beilstein:
969135
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
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vapor pressure
16.85 psi ( 55 °C)
4.86 psi ( 20 °C)
Quality Level
contains
copper as stabilizer
concentration
2.0 M in tert-butyl methyl ether
bp
41-43 °C
density
0.933 g/mL at 25 °C
functional group
alkyl halide
iodo
storage temp.
2-8°C
SMILES string
CI
InChI
1S/CH3I/c1-2/h1H3
InChI key
INQOMBQAUSQDDS-UHFFFAOYSA-N
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General description
The product is 2M solution of iodomethane in tert-butyl methyl ether. Iodomethane also known as methyl iodide is an alkyl halide commonly employed as methylating agent.
Application
- 8-plex LC-MS/MS Analysis of Permethylated N-Glycans Achieved by Using Stable Isotopic Iodomethane.: This research demonstrates the use of iodomethane in stable isotope labeling for the mass spectrometric analysis of permethylated N-glycans. The method enhances the accuracy and sensitivity of glycomic studies (Dong et al., 2019).
- Comparative glycomic profiling of isotopically permethylated N-glycans by liquid chromatography/electrospray ionization mass spectrometry.: The study presents a comparative analysis of N-glycan profiles using isotopically labeled iodomethane, improving the resolution and identification of glycan structures in complex biological samples (Hu et al., 2013).
- Antifungal property of quaternized chitosan and its derivatives.: This paper explores the synthesis of quaternized chitosan derivatives using iodomethane and their subsequent antifungal activities. The results suggest potential applications in biomedical and agricultural fields (Sajomsang et al., 2012).
- Validation of two fluoro-analogues of N,N-dimethyl-2-(2′-amino-4′-hydroxymethyl-phenylthio)benzylamine as serotonin transporter imaging agents using microPET.: This research validates fluoro-analogues of a serotonin transporter imaging agent, synthesized using iodomethane, highlighting its potential in neuroimaging applications (Jarkas et al., 2010).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
-0.4 °F
Flash Point(C)
-18 °C
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Selective mono-methylation of arylacetonitriles and methyl arylacetates by dimethyl carbonate.
Selva M, et al.
Journal of the Chemical Society. Perkin Transactions 1, 10, 1323-1328 (1994)
Xiao-Dan Shi et al.
Food chemistry, 271, 338-344 (2018-09-22)
Dictyophora echinovolvata is a kind of edible mushroom in the Dictyophora genus, of which polysaccharide is an important chemical substance. Herein, three polysaccharide fractions (DEP-4P, DEP-6P and DEP-8P) were prepared from water extract of D. echinovolvata using gradient ethanol precipitation
Microhydration effects on the intermediates of the S(N)2 reaction of iodide anion with methyl iodide.
Keisuke Doi et al.
Angewandte Chemie (International ed. in English), 52(16), 4380-4383 (2013-01-31)
Warayuth Sajomsang et al.
International journal of biological macromolecules, 50(1), 263-269 (2011-11-22)
Five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or N-(3-chloro-2-hydroxypropyl) trimethylammonium chloride (Quat188) as a quaternizing agent under basic condition. The degree of quaternization (DQ) ranged between 28±2% and 90±2%. The antifungal activity was evaluated by using
Riet Bammens et al.
Glycobiology, 25(6), 669-682 (2015-01-23)
The congenital disorders of glycosylation (CDG), a group of inherited diseases characterized by aberrant glycosylation, encompass a wide range of defects, including glycosyltransferases, glycosidases, nucleotide-sugar transporters as well as proteins involved in maintaining Golgi architecture, pH and vesicular trafficking. Mutations
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