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H2882

Supelco

Hydrocortisone 21-hemisuccinate

analytical standard

Synonym(s):

11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate, Cortisol 21-hemisuccinate

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About This Item

Empirical Formula (Hill Notation):
C25H34O8
CAS Number:
2203-97-6
Molecular Weight:
462.53
EC Number:
218-612-3
MDL number:
MFCD00046256
UNSPSC Code:
41116107
PubChem Substance ID:
329815187
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

SMILES string

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)COC(=O)CCC(O)=O)[C@@]4(C)C[C@H](O)[C@H]23

InChI

1S/C25H34O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1

InChI key

VWQWXZAWFPZJDA-CGVGKPPMSA-N

Gene Information

human ... NR3C1(2908)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360D

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000324561
SLCJ5828
SLCC4599
SLBX2928
SLBV7811

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Kelsey A Hart et al.
American journal of veterinary research, 73(1), 68-75 (2011-12-30)
To compare daily endogenous cortisol production rate and the pharmacokinetics of an i.v. bolus of hydrocortisone between neonatal foals and adult horses. 10 healthy full-term 2- to 4-day-old foals and 7 healthy adult horses. Blood samples were collected from each
Takahiro Michiba et al.
Auris, nasus, larynx, 40(2), 162-166 (2012-07-31)
Some patients with sudden sensorineural hearing loss (SSNHL) are frustrated by residual tinnitus even after accomplishment of the treatment for SSNHL. In the present prospective study, we examined patients' backgrounds of sex, laterality and age together with changes in hearing
Susan W Aucott et al.
Pediatrics, 122(4), 775-781 (2008-10-03)
Relative adrenal insufficiency in extremely low birth weight infants may contribute to significant morbidity and death. Our objective was to evaluate the relationship between cortisol concentrations and short-term outcomes. Cortisol concentrations were obtained for 350 intubated, extremely low birth weight
Jian-Hua Shi et al.
Steroids, 75(12), 853-858 (2010-05-18)
Accumulating evidence suggests that adiponectin plays an important role in the genesis of obesity and insulin resistance. Although it has been shown that glucocortocoids (GC) inhibit adiponectin expression in vitro, there exist discrepant results in vivo. In this study, we
Xiaohong Liu et al.
General and comparative endocrinology, 275, 65-72 (2019-02-16)
The pituitary is a central organ of the neuro-endocrine system in fish that plays critical roles in various physiological processes, including stress response and behavior. Although it is known that pituitary hormones can have a direct or indirect influence stimulating
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