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309966

Sigma-Aldrich

Diethyl ether

≥99.9%, suitable for HPLC, inhibitor-free

Synonym(s):

Et2O, Ethoxyethane, Ether, Ethyl ether

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About This Item

Linear Formula:
(CH3CH2)2O
CAS Number:
Molecular Weight:
74.12
Beilstein:
1696894
EC Number:
MDL number:
UNSPSC Code:
12190000
PubChem Substance ID:
NACRES:
NA.07

product name

Diethyl ether, suitable for HPLC, ≥99.9%, inhibitor-free

vapor density

2.6 (vs air)

Quality Level

vapor pressure

28.69 psi ( 55 °C)
8.59 psi ( 20 °C)

Assay

≥99.9%

form

liquid

autoignition temp.

320 °F

purified by

glass distillation

expl. lim.

36.5 %

technique(s)

HPLC: suitable

impurities

≤0.03% water
≤1 ppm peroxides (as H2O2)

evapn. residue

<0.0003%

refractive index

n20/D 1.3530 (lit.)

bp

34.6 °C (lit.)

mp

−116 °C (lit.)

density

0.706 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 218 nm Amax: 1.0
λ: 250 nm Amax: 0.20
λ: 275 nm Amax: 0.04
λ: 300-400 nm Amax: 0.01

application(s)

food and beverages

SMILES string

CCOCC

InChI

1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3

InChI key

RTZKZFJDLAIYFH-UHFFFAOYSA-N

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Application


  • Luminescence of In(III)Cl-etioporphyrin-I.: This study investigates the luminescence properties of In(III)Cl-etioporphyrin-I, employing diethyl ether in the synthesis process to enhance solubility and reaction outcomes (Koptyaev et al., 2023).


  • An efficient synthesis of phosphonated cyclopentenones by NaN(3)-catalyzed three-component reaction between trialkyl phosphites, ethyl arylmethylidenecyanoacetates and dialkyl acetylenedicarboxylates.: Highlights a novel synthesis technique using diethyl ether as a solvent to facilitate the reaction process, crucial for the production of phosphonated cyclopentenones (Ranjbar Derranji and Anary-Abbasinejad, 2024).


  • Antioxidant and Anti-Inflammatory Activities of Phenolic Acid-Rich Extract from Hairy Roots of Dracocephalum moldavica.: Discusses the extraction of phenolic acids using diethyl ether from Dracocephalum moldavica, examining their antioxidant and anti-inflammatory properties (Weremczuk-Jeżyna et al., 2023).

  • [An improved extraction and nonradioactive thin-layer chromatography detection method of mycolic acid].: Describes an improved method for the extraction and analysis of mycolic acid using diethyl ether, enhancing the detection efficiency in biological samples (Xu et al., 2023).


  • A Modified (1)H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples.: Presents a modified NMR quantification method where diethyl ether plays a critical role in the extraction and preparation of samples for precise measurement of ephedrine alkaloids (Li et al., 2023).


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Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 1 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-40.0 °F - closed cup

Flash Point(C)

-40 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lana S Barkawi et al.
Nature protocols, 5(10), 1609-1618 (2010-10-05)
Auxin measurements in plants are critical to understanding both auxin signaling and metabolic homeostasis. The most abundant natural auxin is indole-3-acetic acid (IAA). This protocol is for the precise, high-throughput determination of free IAA in plant tissue by isotope dilution
Eagleson M.
Concise Encyclopedia Chemistry, 471-471 (1994)
Diethyl ether (DEE) as a renewable diesel fuel.
Bailey B, et al.
No. 972978. SAE technical paper (1997)
Oxidation of secondary alcohols in diethyl ether with aqueous chromic acid. Convenient procedure for the preparation of ketones in high epimeric purity.
Brown HC, et al.
The Journal of Organic Chemistry, 36(3), 387-390 (1971)
K H Young et al.
Journal of clinical microbiology, 10(6), 852-853 (1979-12-01)
Ethyl acetate appears to be a satisfactory subsitute solvent for diethyl ether in the Formalin-ether sedimentation technique. In comparative studies, concentration of organisms with ethyl acetate was equal to or greater than that with diethyl ether. No distortion or alteration

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