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360511

Sigma-Aldrich

4-Methyl-2-pentanone

ACS reagent, ≥98.5%

Synonym(s):

Isobutyl methyl ketone, Isopropylacetone, MIBK, Methyl isobutyl ketone

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About This Item

Linear Formula:
(CH3)2CHCH2COCH3
CAS Number:
Molecular Weight:
100.16
Beilstein:
605399
EC Number:
MDL number:
UNSPSC Code:
12352115
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

vapor density

3.5 (vs air)

vapor pressure

15.7 mmHg ( 20 °C)

Assay

≥98.5%

form

liquid

autoignition temp.

840 °F

expl. lim.

1.2-8 %, 93 °F

impurities

≤0.002 meq/g Titr. acid
≤0.100% water

evapn. residue

≤0.0050%

color

APHA: ≤15
clear

refractive index

n20/D 1.395 (lit.)

bp

117-118 °C

mp

−80 °C (lit.)

density

0.801 g/mL at 25 °C (lit.)

SMILES string

CC(C)CC(C)=O

InChI

1S/C6H12O/c1-5(2)4-6(3)7/h5H,4H2,1-3H3

InChI key

NTIZESTWPVYFNL-UHFFFAOYSA-N

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General description

4-Methyl-2-pentanone (Methyl isobutyl ketone (MIBK)) is an organic solvent widely used in various industrial applications. It is used as a solvent for gums, resins, paints, varnishes, lacquers, and nitrocellulose. It is also used as a denaturant and solvent in cosmetic products.

Application

4-Methyl-2-pentanone is used:
  • To prepare (R)-(-)-4-methyl-2-pentanol via asymmetric hydrogenation in the presence of silica-supported starch-polysulfosiloxane-platinum complex (SiO2-ST-Si-S-Pt).
  • In the preparation of jet-fuel-range alkene [C10 and C11 branched alkanes] via aldol condensation reaction with furfural followed by hydrodeoxygenation reaction.
  • Extracting agent for silver, gold and other rare elements from cyanide solutions.

Features and Benefits

4-Methyl-2-pentanone or Methyl isobutyl ketone (MIBK) commonly used diluent or extractant due to its,
  • Low density
  • Viscosity.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Carc. 2 Inhalation - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

57.2 °F - closed cup

Flash Point(C)

14 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jose Ruiz-Jimenez et al.
Journal of chromatography. A, 1616, 460825-460825 (2020-01-12)
Several calibration approaches were evaluated for the quantitation of volatile organic compounds in air using miniaturized exhaustive and non-exhaustive sampling techniques, such as in-tube extraction (ITEX) and solid phase microextraction (SPME) Arrow. Eleven compounds, 2-ethyl-hexanol, hexanal, nonanal, toluene, ethyl-benzene, methyl
H J Shim et al.
Journal of chromatography. B, Biomedical applications, 656(2), 407-414 (1994-06-17)
A high-performance liquid chromatographic method was developed for the simultaneous determination of a new anthracycline, DA-125 (I), and its metabolites (M1, M2, M3, and M4) in rat plasma and urine using fluorescein as an internal standard. Compound I, a prodrug
Matthew D Stout et al.
Toxicology, 244(2-3), 209-219 (2008-01-08)
Methyl isobutyl ketone (MIBK) is primarily used as a denaturant for rubbing alcohol, as a solvent and in the manufacture of methyl amyl alcohol. Inhalation of vapors is the most likely route of exposure in the work place. In order
Sebastian L Riedel et al.
Biotechnology and bioengineering, 110(2), 461-470 (2012-08-21)
Reduced downstream costs, together with high purity recovery of polyhydroxyalkanoate (PHA), will accelerate the commercialization of high quality PHA-based products. In this work, a process was designed for effective recovery of the copolymer poly(hydroxybutyrate-co-hydroxyhexanoate) (P(HB-co-HHx)) containing high levels of HHx
Kieron J Doick et al.
Environmental science & technology, 39(17), 6575-6583 (2005-09-30)
Organic matter is considered to be the single most importantfactor limiting availability and mobility of persistent organic pollutants (POPs) in soil. This study aimed to characterize the distribution of 14C-PCB (congeners 28 and 52) and 14C-PAH (fluoranthene and benzo[a]pyrene) residues

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