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Merck

19899

Sigma-Aldrich

CHAPS 100 mM solution

Synonym(s):

CHAPS solution

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10 G
¥5,350
25 G
¥8,640
100 G
¥23,600
500 G
¥94,600

About This Item

Empirical Formula (Hill Notation):
C32H58N2O7S
CAS Number:
Molecular Weight:
614.88
MDL number:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.25

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description

zwitterionic

Quality Level

form

liquid

mol wt

614.88 g/mol

concentration

100 mM in H2O

technique(s)

protein quantification: suitable

CMC

8 mM

transition temp

cloud point >100 °C

density

1.01 g/mL at 20 °C

storage temp.

2-8°C

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This Item
S1827264103SRE0046
form

powder

form

powder

form

solid

form

-

aggregation number

3-12

aggregation number

3-12

aggregation number

3 - 12, 3-12

aggregation number

3-12

storage temp.

room temp

storage temp.

-

storage temp.

15-25°C

storage temp.

room temp

Quality Level

200

Quality Level

400

Quality Level

100

Quality Level

400

description

anionic

description

-

description

-

description

-

General description

3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate (CHAPS) is a biocompatible surfactant. It is a derivative of cholic acid comprising a hydrophobic cholesterol-like skeleton possessing three hydroxyl groups and a zwitterionic aliphatic tail.[1]

Application

CHAPS 100 mM solution has been used as a component of lysis buffer for the extraction of proteins from goat endometrial epithelial cells (EECs)[2] and liver tissue.[3]

Biochem/physiol Actions

3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate (CHAPS) exhibits the properties of both sulfobetaine-type surfactants and bile salts. It is involved in the protein extraction process for proteomic analysis and reconstitution of membrane proteins into lipid vesicles (proteoliposomes). CHAPS is broadly used in biochemistry for membrane protein and receptor isolation and purification. It is conveniently used in pharmaceuticals and medicines due to its biocompatibility, noncharged character, nondenaturing, and disaggregating properties.[1]

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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