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256A-1

Sigma-Aldrich

Gastrin Rabbit Polyclonal Antibody

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1 EA
$80.20

$80.20


Estimated to ship onMarch 18, 2025


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1 EA
$80.20

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$80.20


Estimated to ship onMarch 18, 2025


Request a Bulk Order

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (256A-14)
vial of 0.5 mL concentrate (256A-15)
bottle of 1.0 mL predilute (256A-17)
vial of 1.0 mL concentrate (256A-16)
bottle of 7.0 mL predilute (256A-18)

General description

Gastrin is a polypeptide hormone produced by G-cells in the gastric antrum and duodenal mucosa that serves as an important regulator of gastric acid secretion.[1] Gastrin is useful for the identification of gastrin-secreting non-neoplastic and neoplastic neuroendocrine cells.[2][3] Anti-Gastrin antibody gives positive staining of G-cells of human antral/pyloric mucosa and cells producing gastrin or a structural gastrin analogue as is seen in the stomach; no staining of other cells or tissue types has been observed. This antibody may react with sulfated and non-sulfated forms of gastrin. The antibody cross-reacts with more than 50% of the present choleocystokinin octapeptide.

Quality


IVD

IVD

IVD

RUO

Linkage

Gastrin (polyclonal) Positive Control Slides, Product No. 256S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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J Müller et al.
The American journal of surgical pathology, 11(12), 909-917 (1987-12-01)
Immunohistochemical, histochemical, and morphometrical studies of six gastric carcinoid tumors and their possible precursor lesions in gastric mucosa are reported. All tumors, presenting successively at our institute, occurred in the corpus mucosa of 45- to 78-year-old patients. Two neoplasms had
L Bornstein-Quevedo et al.
Human pathology, 32(11), 1252-1256 (2001-12-01)
Carcinoid tumors of the ampulla of Vater (ACs) differ from duodenal carcinoid tumors (DCs). A search for AC and DC was made between 1980 and 2000. The clinicopathologic features and follow-up were assessed. Immunohistochemistry for panneuroendocrine markers, hormone products, proliferating
M E Herrmann et al.
Archives of pathology & laboratory medicine, 124(6), 832-835 (2000-06-03)
The term primary lymph node gastrinoma was first used to describe a group of patients with gastrin-producing tumors present in lymph nodes located in a well-defined anatomic region. The patients had no known primary tumors in the pancreas or gastrointestinal
Gastrin and Gastric Cancer.
Smith, Jill P et al.
Cellular and molecular gastroenterology and hepatology, 75-83, 75-83 (2017)
Expression of gastrin and its receptor in human gastric cancer tissues.
Hur, Keun et al
Journal of Cancer Research and Clinical Oncology, 132,2, 85-91 (2006)

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