A255

A-77636 hydrochloride hydrate

≥98% (HPLC), solid

• Synonym(s): (−)-(1R,3S)-3-Adamantyl-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyran hydrochloride hydrate
• Empirical Formula (Hill Notation): C₂₀H₂₇NO₃ · HCl · xH₂O
• CAS Number: 145307-34-2
• Molecular Weight: 365.89 (anhydrous basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277883
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated; protect from light
• color: white to off-white
• solubility: H₂O: >10 mg/mL
• storage temp.: −20°C
• SMILES string: O.Cl.NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)C34CC5CC(CC(C5)C3)C4
• InChI: 1S/C20H27NO3.ClH.H2O/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H;1H2/t11?,12?,13?,17-,18-,20?;;/m0../s1
• InChI key: KNACNUUSUYTFDY-LIWDBWMRSA-N
• Gene Information: human ... DRD1(1812)

Description

Biochem/physiol Actions

Potent, orally active D₁ dopamine receptor agonist.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Caution

Hygroscopic, photosensitive, and oxygen-sensitive. Solutions should be freshly prepared.

Legal Information

Manufactured and sold under exclusive license from Abbott Laboratories.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves