A7155
p-Aminobenzamidine–Agarose
saline suspension
Synonym(s):
p-ABA
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form
saline suspension
Quality Level
matrix
cross-linked 4% beaded agarose
matrix activation
cyanogen bromide
matrix attachment
amino to carboxyl of spacer
matrix spacer
7 atoms
capacity
≥10 mg/mL binding capacity (trypsin)
storage temp.
2-8°C
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Application
p-Aminobenzamidine-Agarose (pABA) can be used as an affinity ligand to bind and remove serine proteases in addition to Ca2+-binding proteins. It has also been used in medical applications as a tool for the purification of non-protease proteins.
Physical form
Suspension in 0.5 M NaCl containing preservative
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
482.0 °F - closed cup
Flash Point(C)
250 °C - closed cup
Certificates of Analysis (COA)
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A Anisowicz et al.
Molecular medicine (Cambridge, Mass.), 2(5), 624-636 (1996-09-01)
Using differential display (DD), we discovered a new member of the serine protease family of protein-cleaving enzymes, named protease M. The gene is most closely related by sequence to the kallikreins, to prostate-specific antigen (PSA), and to trypsin. The diagnostic
J F Eccleston et al.
The Journal of biological chemistry, 268(36), 27012-27019 (1993-12-25)
Single turnover and equilibrium binding measurements on the interaction of Gly-12 and Pro-12 Ras.GTP with the catalytic domains of the GTPase-activating proteins, p120-GAP and neurofibromin, have been made utilizing fluorescent 2'(3')O-(N-methylanthraniloyl)-nucleotides. These have enabled the equilibrium dissociation constants (Kd) for
Andrew M Petros et al.
Journal of medicinal chemistry, 62(8), 4120-4130 (2019-04-02)
Apolipoprotein E is a 299-residue lipid carrier protein produced in both the liver and the brain. The protein has three major isoforms denoted apoE2, apoE3, and apoE4 which differ at positions 112 and 158 and which occur at different frequencies
Anup K Upadhyay et al.
Acta crystallographica. Section F, Structural biology communications, 73(Pt 3), 116-122 (2017-03-16)
The rapid spread of the recent Zika virus (ZIKV) epidemic across various countries in the American continent poses a major health hazard for the unborn fetuses of pregnant women. To date, there is no effective medical intervention. The nonstructural protein
Biochemical and molecular modeling analysis of the ability of two p-aminobenzamidine-based sorbents to selectively purify serine proteases (fibrinogenases) from snake venoms.
De-Simone, S.G., et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 822(1-2), 1-9 (2005)
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