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Key Documents

L5502

Sigma-Aldrich

Lys-Lys dihydrochloride

≥98% (TLC)

Synonym(s):

Dilysine

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About This Item

Empirical Formula (Hill Notation):
C12H26N4O3 · 2HCl
CAS Number:
Molecular Weight:
347.28
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Lys-Lys dihydrochloride,

Assay

≥98% (TLC)

form

powder

color

white

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

Cl.NCCCCC(N)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C12H26N4O3.ClH/c13-7-3-1-5-9(15)11(17)16-10(12(18)19)6-2-4-8-14;/h9-10H,1-8,13-15H2,(H,16,17)(H,18,19);1H

InChI key

ROGKVZGKYWMMAT-UHFFFAOYSA-N

Application

Lysyllysine (Lys-Lys) may be used in studies of prebiotically relevant Salt-Induced Peptide Formation (SIPF) and in for physical chemical analysis.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kristof Plankensteiner et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 35(5), 411-419 (2005-10-19)
"Mutual" amino acid catalysis of glycine on the formation of ditryptophan, dilysine, and diserine in the prebiotically relevant Salt-Induced Peptide Formation (SIPF) Reaction was investigated varying the starting concentration and chirality of the educt amino acid, and analyzing the increase
Jayasri Das Sarma et al.
The Journal of biological chemistry, 277(23), 20911-20918 (2002-04-04)
To define further the mechanisms of gap junction protein (connexin (Cx)) oligomerization without pharmacologic disruption, we have examined the transport and assembly of connexin constructs containing C-terminal di-lysine-based endoplasmic reticulum (ER) (HKKSL) or ER-Golgi intermediate compartment (AKKFF) targeting sequences. By
D Nurizzo et al.
Biochemistry, 40(6), 1616-1623 (2001-05-01)
Human transferrin (Tf) is responsible for the binding and transport of iron in the bloodstream of vertebrates. Delivery of this bound iron to cells occurs by a process of receptor-mediated endocytosis during which Tf releases its iron at the reduced
F L Henriquez et al.
Parasitology, 131(Pt 2), 169-179 (2005-09-10)
Studies using antibodies to immunolocalize the Toxoplasma gondii dense granule protein GRA3, have shown that this protein associates strongly with the parasitophorous vacuole membrane (PVM). However, as there was no predicted membrane-spanning domain this highlighted an unanswered paradox. We demonstrate
Hesso Farhan et al.
Journal of cell science, 121(Pt 6), 753-761 (2008-02-21)
The C-terminus of GABA transporter 1 (GAT1, SLC6A1) is required for trafficking of the protein through the secretory pathway to reach its final destination, i.e. the rim of the synaptic specialization. We identified a motif of three hydrophobic residues (569VMI571)

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