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SML0270

Sigma-Aldrich

NSC 632839

≥98% (HPLC)

Synonym(s):

3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride, 4-Piperidione,3,5-bis[(4-methylphenyl)methylene] hydrochloride, F6

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About This Item

Empirical Formula (Hill Notation):
C21H21NO · HCl
CAS Number:
157654-67-6
Molecular Weight:
339.86
MDL number:
MFCD09753281
UNSPSC Code:
12352200
PubChem Substance ID:
329825278
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

faintly yellow to dark yellow

solubility

DMSO: ≥2 mg/mL (warmed)

storage temp.

2-8°C

SMILES string

Cl.Cc1ccc(cc1)\C=C2/CNC\C(=C/c3ccc(C)cc3)C2=O

InChI

1S/C21H21NO.ClH/c1-15-3-7-17(8-4-15)11-19-13-22-14-20(21(19)23)12-18-9-5-16(2)6-10-18;/h3-12,22H,13-14H2,1-2H3;1H/b19-11+,20-12+;

InChI key

ZOKZLTXPTLIWOJ-BYCVLTJGSA-N

Biochem/physiol Actions

NSC 632839 is an ubiquitin isopeptidases inhibitor targets the ubiquitinproteasome system (UPS).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The minimal neural correlate of the conscious state, regardless of the neural activity correlated with the ever-changing contents of experience, has still not been identified. Different attempts have been made, mainly by comparing the normal waking state to seemingly unconscious
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Glioblastoma multiforme (GBM) is an aggressive brain tumor driven by cells with hallmarks of neural stem (NS) cells. GBM stem cells frequently express high levels of the transcription factors FOXG1 and SOX2. Here we show that increased expression of these
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Although generally indolent, follicular lymphoma (FL) sometimes pursues a more aggressive course leading to early death. B-cell-specific Mo-MLV insertion site-1 (BMI1) is a member of the polycomb group (PcG) proteins that confer stem cell properties through gene silencing. We used
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