SML3547

8RK59

≥98% (HPLC)

• Synonym(s): (S)-1-Xyano-N-(5-(2-(4-(4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2′,1′-f][1,3,2]diazaborinin-10-yl)butyl)-1H-1,2,3-triazol-1-yl)acetyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)pyrrolidine-3-carboxamide
• Empirical Formula (Hill Notation): C₃₃H₃₉BF₂N₁₀O₂S
• CAS Number: 2705841-53-6
• Molecular Weight: 688.60
• UNSPSC Code: 41104922
• UNSPSC Code: 12352200
• NACRES: NA.21

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: , Faint orange to red
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C([C@H]1CCN(C#N)C1)NC2=NC3=C(S2)CN(C(CN4N=NC(CCCCC(C5=C(C)C=C(C)N5[B-]6(F)F)=C7[N+]6=C(C)C=C7C)=C4)=O)CC3

Description

Biochem/physiol Actions

8RK59 is a cellularly active covalent fluorescent probe that targets selectively active UCHL1 (ubiquitin carboxy-terminal hydrolase L1). 8RK59 selectively and spatiotemporally report UCHL1 activity in zebrafish embryos.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable