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Merck
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Key Documents

Z4277

Sigma-Aldrich

Zileuton

≥98% (HPLC)

Synonym(s):

(±)-N-hydroxy-N-(1-benzo[b]thien-2-ylethyl)urea

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About This Item

Empirical Formula (Hill Notation):
C11H12N2O2S
CAS Number:
Molecular Weight:
236.29
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥20 mg/mL at ~60 °C (warm up to 60 C for 5min)

originator

Abbott

storage temp.

room temp

SMILES string

CC(N(O)C(N)=O)c1cc2ccccc2s1

InChI

1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)

InChI key

MWLSOWXNZPKENC-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item
1724656Z0877B9688
Zileuton ≥98% (HPLC)

Z4277

Zileuton

Zileuton United States Pharmacopeia (USP) Reference Standard

1724656

Zileuton

Zotepine

Z0877

Zotepine

Pizotifen ≥98% (HPLC)

B9688

Pizotifen

form

powder

form

-

form

powder

form

powder

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

room temp

solubility

DMSO: ≥20 mg/mL at ~60 °C (warm up to 60 C for 5min)

solubility

-

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: ≥8 mg/mL

originator

Abbott

originator

-

originator

Astellas

originator

Novartis

Biochem/physiol Actions

Zileuton is an anti-asthmatic, an inhibitor of 5-lipoxygenase; the initial enzyme in the biosynthesis of leukotrienes from arachidonic acid.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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