Skip to Content
Merck
All Photos(1)

Key Documents

47774

Supelco

Menaquinone (K2)

analytical standard

Synonym(s):

Vitamin K2, Menaquinone 4, Menatetrenone

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C31H40O2
CAS Number:
Molecular Weight:
444.65
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:

grade

analytical standard

Quality Level

CofA

current certificate can be downloaded

feature

standard type fat soluble vitamin

packaging

ampule of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

-10 to -25°C

SMILES string

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(C)C(=O)c2ccccc2C1=O

InChI

1S/C31H40O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,12,14,16,18-20H,9-11,13,15,17,21H2,1-6H3/b23-14+,24-16+,25-20+

InChI key

DKHGMERMDICWDU-GHDNBGIDSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Menaquinone (K2), a vitamin K2 homologue with four isoprene units. It has been reported to enhance bone formation and plays a vital role in the production of blood coagulation factors.

Application

Menaquinone may be used as a reference standard for the determination of menaquinone in human plasma using liquid chromatography with tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Simple and sensitive determination of menatetrenone and its epoxide metabolite in human plasma.
Kang W, et al.
Journal of Pharmaceutical and Biomedical Analysis, 44(5), 1178-1182 (2007)
Effects of menatetrenone on bone loss induced by ovariectomy in rats.
Akiyama Y, et al.
Japanese Journal of Pharmacology, 62(2), 145-153 (1993)
Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor κ activation.
Ozaki I, et al.
Clinical Cancer Research, 13(7), 2236-2245 (2007)
T Terachi et al.
Journal of animal science, 89(4), 1056-1061 (2010-12-21)
The effect of several vitamin K homologs on plasma vitamin K concentration was determined to assess their potential as a vitamin K supplement for adult horses. Sixteen Thoroughbred horses consisting of 8 mares and 8 geldings, aged 8.4 ± 3.6
Mariko Ochiai et al.
Nephron. Clinical practice, 117(1), c15-c19 (2010-08-07)
A low level of intact parathyroid hormone (PTH) is an indicator of adynamic bone disease in hemodialysis patients, and is associated with a significant increase of all-cause mortality. Thus, effective treatment for adynamic bone disease is required. We previously investigated

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service