추천 제품
Quality Level
분석
≥98.0% (HPLC)
형태
powder or crystals
광학 활성
[α]/D -5.5±1.0°, c = 1 in DMF
반응 적합성
reaction type: Fmoc solid-phase peptide synthesis
응용 분야
peptide synthesis
작용기
Fmoc
저장 온도
−20°C
SMILES string
Cc1c(C)c(c(C)c2CC(C)(C)Oc12)S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCC3c4ccccc4-c5ccccc35)C(O)=O
InChI
1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1
InChI key
HNICLNKVURBTKV-NDEPHWFRSA-N
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일반 설명
Fmoc-Arg(Pbf)-OH is used as a building block in peptide synthesis, providing protection to specific functional groups while allowing for efficient peptide bond formation.
애플리케이션
Fmoc-Arg(Pbf)-OH is a Fmoc-protected amino acid derivative that can be used to create arginine-containing peptides. The 2,2,4,6,7-pentamethyIdlhydrobenzofuran-5-sulfonyl group (Pbf) can be easily cleaved by trifluoroacetic acid (TFA).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Side-Chain Unprotected Fmoc-Arg/His/Tyr-OH Couplings and Their Application in Solid-Phase Peptide Synthesis through a Minimal-Protection/Green Chemistry Strategy
Organic Process Research & Development, 26 (2022)
A cobaltocenium?peptide bioconjugate shows enhanced cellular uptake and directed nuclear delivery.
Angewandte Chemie (International Edition in English), 44(16), 2429-2432 (2005)
Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.
Nature Biotechnology, 18(2), 187-187 (2000)
The 2, 2, 4, 6, 7-pentamethyldihydrobenzofuran-5-sulfonyl group (Pbf) as arginine side chain protectant.
Tetrahedron Letters, 34(49), 7829-7832 (1993)
Solid phase synthesis, radiolabeling and biological evaluation of a 99mTc-labeled αVβ3 tripeptide (RGD) conjugated to DOTA as a tumor imaging agent.
Cancer Biology & Therapy, 11(10), 893-901 (2011)
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