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Merck
모든 사진(1)

주요 문서

A8309

Sigma-Aldrich

Acethydrazide

90%

동의어(들):

Acetic acid hydrazide, Acetylhydrazine

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About This Item

Linear Formula:
CH3CONHNH2
CAS Number:
Molecular Weight:
74.08
Beilstein:
506165
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

90%

양식

flakes

불순물

<10% acetic acid

bp

129 °C/18 mmHg (lit.)

mp

58-68 °C (lit.)

SMILES string

CC(=O)NN

InChI

1S/C2H6N2O/c1-2(5)4-3/h3H2,1H3,(H,4,5)

InChI key

OFLXLNCGODUUOT-UHFFFAOYSA-N

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일반 설명

Acethydrazide is an organic building that undergo catalytic hydrogenation to produce N′-methyl acethydrazide (MAH).

애플리케이션

Acethydrazide can be used in the synthesis of (E)-N′-(2-hydroxybenzylidene)acetohydrazide, an ONO pincer ligand.

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point (°F)

235.4 °F - closed cup

Flash Point (°C)

113 °C - closed cup

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

이미 열람한 고객

N E Preece et al.
Journal of chromatography, 573(2), 227-234 (1992-01-17)
Plasma and liver levels of hydrazine were determined at 10, 30, 90 and 270 min in rats given 0.09, 0.27, 0.84 and 2.53 mmol of hydrazine per kg body weight orally by capillary gas chromatography-mass spectrometry of its pentafluorobenzaldehyde adduct
Victoria E Richards et al.
Toxicological sciences : an official journal of the Society of Toxicology, 82(1), 318-332 (2004-07-30)
Hydrazine (HD) and acetylhydrazine (AcHD) are metabolites of the antituberculosis drug isoniazid (INH) that have been implicated in INH-induced liver damage. The hepatotoxicity of AcHD and HD were compared in adult male C57Bl/6J mice by evaluating hepatic histopathology, plasma biochemistry
Mixed valent/geometry, linear, tetranuclear nickel complex bearing ONO pincer ligand exhibiting hitherto unknown ligation mode.
Shalini C, et al.
Polyhedron (2017)
D J Fort et al.
Teratogenesis, carcinogenesis, and mutagenesis, 10(6), 463-476 (1990-01-01)
The developmental toxicity of isoniazid (INH) and the metabolites acetylhydrazide (AH) and isonicotinic acid (INA) were examined with the frog embryo teratogenesis assay-Xenopus (FETAX). Late Xenopus laevis blastulae were exposed to INH, AH, and INA for 96 h in two
N E Preece et al.
Biochemical pharmacology, 41(9), 1319-1324 (1991-05-01)
15N-NMR has been used to study the metabolism of hydrazine in rats in vivo. Single doses of [15N2]hydrazine (2.0 mmol/kg: 98.6% g atom) were administered to rats and urine collected for 24 hr over ice. A number of metabolites were

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