857128P
Avanti
18:0 Lyso PA
Avanti Research™ - A Croda Brand
동의어(들):
1-octadecanoyl-sn-glycero-3-phosphate (sodium salt); stearoyl lysophosphatidic acid; PA(18:0/0:0); 18:0 LPA; s-LPA; 110680
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
실험식(Hill 표기법):
C21H42O7PNa
CAS Number:
Molecular Weight:
460.52
UNSPSC 코드:
51191904
NACRES:
NA.25
추천 제품
설명
1-stearoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
분석
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
양식
powder
포장
pkg of 1 × 25 mg (857128P-25mg)
제조업체/상표
Avanti Research™ - A Croda Brand
지질 유형
cardiolipins
phospholipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]
InChI key
YJQFVAZHPIBPHN-VEIFNGETSA-M
일반 설명
Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells. 18:0 Lyso PA has stearic acid at sn-1 and a hydroxyl group at sn-2 position.
애플리케이션
18:0 Lyso PA is suitable for use:
- to determine the extraction recovery of LPA at neutral pH and acidic pH by chromatographic method
- to use as internal standard to study the role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis
- to investigate its effects on clathrin?dependent endocytosis
생화학적/생리학적 작용
Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).
포장
5 mL Amber Glass Screw Cap Vial (857128P-25mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
또한 이 제품과 함께 일반적으로 구입
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Ailte I, et al.
Traffic, 18(3), 176-191 (2017)
Lysophosphatidic acid triggers apoptosis in HeLa cells through the upregulation of tumor necrosis factor receptor superfamily member 21
Dong Y, et al.
Mediators of Inflammation, 2017 (2017)
Quantitative determination of lysophosphatidic acid by LC/ESI/MS/MS employing a reversed phase HPLC column
Shan L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 864(1-2), 22-28 (2008)
Ieva Ailte et al.
Scientific reports, 6, 30336-30336 (2016-07-28)
Shiga toxin (Stx), an AB5 toxin, binds specifically to the neutral glycosphingolipid Gb3 at the cell surface before being transported into cells. We here demonstrate that addition of conical lysophospholipids (LPLs) with large head groups inhibit Stx binding to cells
Mohamad Navab et al.
Journal of lipid research, 54(12), 3403-3418 (2013-10-03)
We recently reported that levels of unsaturated lysophosphatidic acid (LPA) in the small intestine significantly correlated with the extent of aortic atherosclerosis in LDL receptor-null (LDLR⁻/⁻) mice fed a Western diet (WD). Here we demonstrate that WD increases unsaturated (but
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.