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860571P

Avanti

C24:1 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/24:1)

Avanti Research™ - A Croda Brand 860571P, powder

동의어(들):

3-O-sulfo-D-galactosyl-β1-1′-N-nervonoyl-D-erythro-sphingosine (ammonium salt), (synthetic)

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About This Item

실험식(Hill 표기법):
C48H94N2O11S
CAS Number:
1246355-69-0
Molecular Weight:
907.33
UNSPSC 코드:
12352211
NACRES:
NA.25

양식

powder

포장

pkg of 1 × 1 mg (860571P-1mg)

제조업체/상표

Avanti Research™ - A Croda Brand 860571P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H]([C@H]1CO)O.[NH4+]

InChI

1S/C48H91NO11S.H3N/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2)40-58-48-46(54)47(60-61(55,56)57)45(53)43(39-50)59-48;/h17-18,35,37,41-43,45-48,50-51,53-54H,3-16,19-34,36,38-40

InChI key

MQKRPROAXITSNY-ZLGWSYPSSA-N

일반 설명

3-O-sulfogalactosylceramide, also known as sulfatide is a sulfoglycolipid. It was first isolated from the human brain. Sulfatide is present mainly in the cellular membrane, Golgi apparatus and lysosomes. It is produced by ceramide galactosyltransferase and cerebroside sulfotransferase.

애플리케이션

C24:1 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/24:1) has been used in the stimulation of leukocyte mono-immunoglobulin (Ig)-like receptor 5 (LMIR5). It may be used as a lipid standard in matrix-assisted laser desorption ionization (MALDI) analysis of mouse brain tissues.

생화학적/생리학적 작용

Sulfatide plays a vital role in the biological functions of microbial infection, hemostasis, nervous system and immune system. Accumulation of lysosomal sulfatide is associated with metachromatic leukodystrophy (MLD). Sulfatide is implicated in protein trafficking, signal transduction and neuronal cell differentiation.

포장

5 mL Amber Glass Screw Cap Vial (860571P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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제품 번호
설명
가격

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Vongsavanh Phongsisay et al.
Molecular immunology, 66(2), 463-471 (2015-05-30)
Cholera toxin (CTX) is a virulent factor of Vibrio cholerae that causes life-threatening diarrheal disease. Its non-toxic subunit CTB has been extensively studied for vaccine delivery. In immune cells, CTB induces a number of signaling molecules related to cellular activation
Medical Applications of Mass Spectrometry (2011)
Medical Applications of Mass Spectrometry (2011)
Tadanobu Takahashi et al.
Journal of lipid research, 53(8), 1437-1450 (2012-05-24)
Sulfatide is 3-O-sulfogalactosylceramide that is synthesized by two transferases (ceramide galactosyltransferase and cerebroside sulfotransferase) from ceramide and is specifically degraded by a sulfatase (arylsulfatase A). Sulfatide is a multifunctional molecule for various biological fields including the nervous system, insulin secretion
Jarod A Fincher et al.
The Journal of comparative neurology, 527(13), 2101-2121 (2018-10-26)
Mass spectrometry imaging (MSI) is capable of detection and identification of diverse classes of compounds in brain tissue sections, whereas simultaneously mapping their spatial distributions. Given the vast array of chemical components present in neurological systems, as well as the

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