20801
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
meets analytical specification of Ph. Eur., BP, NF, 98-100.5% (calc with ref. to anhyd. subst.)
동의어(들):
β,β,β-Trichloro-tert-butyl alcohol hemihydrate, ‘Acetone chloroform’, ‘Chlorobutanol’
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
Linear Formula:
Cl3CC(CH3)2OH · 0.5H2O
CAS Number:
Molecular Weight:
186.46
Beilstein:
878167
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.21
추천 제품
Quality Level
분석
98-100.5% (calc with ref. to anhyd. subst.)
형태
solid
품질
meets analytical specification of Ph. Eur., BP, NF
불순물
≤0.002% heavy metals (as Pb)
4.5-5.5% water (Karl Fischer)
무기 잔류물
≤0.1% (as SO4)
mp
76-80 °C
음이온 미량물
chloride (Cl-): ≤100 mg/kg
응용 분야
pharmaceutical (small molecule)
SMILES string
O.CC(C)(O)C(Cl)(Cl)Cl.CC(C)(O)C(Cl)(Cl)Cl
InChI
1S/2C4H7Cl3O.H2O/c2*1-3(2,8)4(5,6)7;/h2*8H,1-2H3;1H2
InChI key
WRWLCXJYIMRJIN-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) is a preservative used as a standard for quantifying preservatives in pharmaceutical formulations by using capillary electrophoretic method. It has also been used to anesthetize leeches for preparing c-DNA library from regenerating retzius cells.
생화학적/생리학적 작용
Chlorobutanol or 1,1,1-Trichloro-2-methyl-2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties. It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
212.0 °F - closed cup
Flash Point (°C)
100 °C - closed cup
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
S Korneev et al.
Invertebrate neuroscience : IN, 3(2-3), 185-192 (1998-10-23)
We have constructed a subtractive cDNA library from regenerating Retzius cells of the leech, Hirudo medicinalis. It is highly enriched in sequences up-regulated during nerve regeneration. Sequence analysis of selected recombinants has identified both novel sequences and sequences homologous to
Elena S Novitskaya et al.
Clinics in dermatology, 29(3), 295-299 (2011-04-19)
Identifying contact allergens in ophthalmic medications can be a challenging and daunting experience. We summarize data on topical ophthalmic medications with the potential to cause periorbital contact dermatitis and allergic conjunctivitis, highlighting current dilemmas and controversies in this area. The
K Hermsmeyer et al.
The American journal of physiology, 230(2), 306-310 (1976-02-01)
The negative inotropic effect of a commonly used formulation of bradykinin (Sandoz BRS-640) was found to be due to chlorobutanol, a constituent of the preparation. Solutions containing up to 100 mug of crystalline bradykinin/ml had no effect on tension or
Małgorzata Jaworska et al.
Journal of separation science, 28(2), 137-143 (2005-03-10)
Preservatives are used to protect pharmaceutical formulations from microbial attack during the period of administration to the patient. Because of their biological activity, preservatives have to be identified and assayed according to the same rules as apply to active components.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.