추천 제품
Grade
analytical standard
분석
≥95.0% (LC/MS)
광학 활성
[α]/D -12±2°, c = 0.1 in methanol
유통기한
limited shelf life, expiry date on the label
응용 분야
clinical testing
형식
neat
저장 온도
−20°C
SMILES string
[O-]C(C([H])([H])[C@](OC(/C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O
일반 설명
trans-2-Tetradecenoyl-L-carnitine, belonging to the class of acylcarnitines, serves as a specific diagnostic metabolite biomarker, which increases in very long-chain acyl CoA dehydrogenase (VLCAD) deficiency, existing as a long-chain β-oxidation defect in newborns.
애플리케이션
trans-2-Tetradecenoyl-L-carnitine may be used as an analytical reference standard in the following:
- Quantification of the analyte in biological samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC/MS/MS).
- Quantification of the analyte in dried blood spots using chip-based nanoelectrospray source coupled with high resolution mass spectrometry (chip-based nanoESI- HRMS) and targeted liquid chromatography-tandem mass spectrometry (LC/MS/MS).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Screening newborns for metabolic disorders based on targeted metabolomics using tandem mass spectrometry
Annals of pediatric endocrinology & metabolism, 20(3), 119-119 (2015)
Tandem mass spectrometry screening for very long-chain acyl-CoA dehydrogenase deficiency: the value of second-tier enzyme testing
The Journal of Pediatrics, 157(4), 668-673 (2010)
Quantification of metabolites in dried blood spots by direct infusion high resolution mass spectrometry
Analytica Chimica Acta, 979, 45-50 (2017)
Differences between acylcarnitine profiles in plasma and bloodspots
Molecular Genetics and Metabolism, 110(1-2), 116-121 (2013)
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