A8452

Monoclonal Anti-α-Fetoprotein (AFP) antibody produced in mouse

ascites fluid, clone C3

• 동의어(들): Afp Antibody, Afp Antibody - Monoclonal Anti-α-Fetoprotein (AFP) antibody produced in mouse, Alpha Fetoprotein Antibody
• MDL number: MFCD00162111
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: ascites fluid
• 항체 생산 유형: primary antibodies
• 클론: C3, monoclonal
• 포함: 15 mM sodium azide
• 종 반응성: pig, canine, human
• 반응하면 안 됨: mouse, cat, rat, bovine
• 기술: dot blot: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500 using human fetal liver; indirect ELISA: suitable
• 동형: IgG2a
• UniProt 수납 번호: P02771
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... AFP(174)

설명

일반 설명

α-Fetoprotein (AFP) is a one of the main glycoprotein present in the fetal liver, gastrointestinal tract, and yolk sac. AFP levels in amniotic fluid have been used as biomarkers for anencephaly and spina bifida.

Monoclonal Anti-α-Fetoprotein (AFP) (mouse IgG2a isotype) is derived from the C3 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified human α-fetoprotein.

면역원

human α-fetoprotein

애플리케이션

Monoclonal Anti-α-Fetoprotein (AFP) antibody produced in mouse has been used in:

• enzyme-linked immunosorbent assay (ELISA)
• dot blot
• immunocytochemistry
• immunofluorescence
• immunocytochemistry

Mouse Monoclonal Anti-α-Fetoprotein has been used for immunocytochemistry. The product can also be used for dot blot and indirect ELISA.

생화학적/생리학적 작용

Increased concentrations of α-fetoprotein (AFP) in serum are less common in patients with malignancies of the gastrointestinal tract and of other organ systems with massive hepatic metastases. Hence, AFP determination is useful for the diagnosis of certain germ line tumors that contain yolk sac structures (testicular and ovarian tumors), hepatocellular carcinoma (hepatoma), and some malignant tumors of the gastrointestinal tract. AFP serves as an important marker for certain genetic and embryonic defects. Routine screening of pregnancies with a risk of neural tube defects (spina bifida, anencephaly, and Down′s syndrome) may be facilitated by the monitoring of AFP levels.

표적 설명

AFP is a plasma protein found highly expressed in the human fetus where it functions to block the transport of estradiol across the placenta.

물리적 형태

The product is provided as ascites fluid with 0.1% sodium azide as a preservative.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable