D0443

Dextranase from Chaetomium erraticum

• 동의어(들): Dextranase Plus L, 1,6-α-D-Glucan 6-glucanohydrolase
• CAS Number: 9025-70-1
• 효소 위원회 번호: 3.2.1.11 (BRENDA, IUBMB)
• EC Number: 232-803-9
• MDL number: MFCD00130940
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 형태: solution
• Quality Level: 300
• 저장 온도: 2-8°C

설명

일반 설명

A product of Novozymes Corp.

Dextranase is generated by many microorganisms, including bacteria, filamentous fungi, and yeast.

애플리케이션

Dextranase from Chaetomium erraticum has been used:

• in microcarrier dissolution to produce multicellular 3D spheroids for drug discovery
• in in vitro digestion of extracellular polysaccharide (EPS) from the bacterial isolates
• in a study to investigate the immobilization of dextranase
• to investigate the optimization of process conditions for enzymatic modification of alternan

생화학적/생리학적 작용

Dextranase is an endodextranase that hydrolyzes α-(1,6)-glycosidic linkages in dextran. It has many industrial and clinical applications such as food processing, sugar modification, and medicine preparation. Dextranase is widely used to produce alternated sugar beet and isomaltooligosaccharides (IMOs), a prebiotic functional food. The low molecular weight dextran obtained from dextranase serves as a synthetic blood volume expander. Dextranase can be coupled to antibodies for the detection of tumor cells. It prevents the occurrence of dental plaques by depolymerizing microbial dextran deposits in teeth. Hence, it is used in dental care products.

제조 메모

A fungal dextranase produced by submerged fermentation of Chaetomium erraticum.

분석 메모

Stable in the pH range of 3-7 and at temperatures up to approx. 70 °C. For most applications, the preferred conditions are pH 5-6 and a temperature of 50-60 °C.

기타 정보

View more information on enzymes for complex carbohydrate analysis at www.sigma-aldrich.com/enzymeexplorer

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H334
• 예방조치 성명서: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)