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Merck
모든 사진(6)

주요 문서

F3418

Sigma-Aldrich

Monoclonal Anti-Cytokeratin, pan−FITC antibody produced in mouse

clone C-11, purified immunoglobulin, buffered aqueous solution

동의어(들):

Monoclonal Anti-Pan Cytokeratin

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

결합

FITC conjugate

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

C-11, monoclonal

양식

buffered aqueous solution

종 반응성

bovine, mouse, frog, human, kangaroo rat, rat

저장 조건

protect from light

기술

direct immunofluorescence: 1:50 using PtK2 cells
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50 using human placenta
western blot: suitable

동형

IgG1

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

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관련 카테고리

일반 설명

Cytokeratins are the intermediate filaments of endocrine cells. These proteins belong to the intermediate filament (10 nm) superfamily of cytoskeletal proteins. Cytokeratins are the largest and most complex group of intermediate filaments. The family consists of at least 30 proteins with molecular weights ranging from 40kDa to 68kDa.

면역원

keratin-enriched preparation from cultured human epidermoid carcinoma cell line A431.

애플리케이션

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (1 paper)
Monoclonal Anti-Cytokeratin, pan−FITC antibody has been used in immunocytochemistry and has also been used to visualize lung epithelial cells.

생화학적/생리학적 작용

Cytokeratins helps in subtyping several kinds of epithelial differentiation or for narrowing possible sites of origin for metastatic carcinomas. Cytokeratins may play an important role in transhepatic transport and canalicular secretion.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Potential biological role of transforming growth factor-beta in human congenital kidney malformations
Yang Su P, et al.
The American Journal of Pathology, 157(5), 1633-1647 (2000)
Autocrine GABA signaling distinctively regulates phenotypic activation of mouse pulmonary macrophages
Januzi L, et al.
Cellular Immunology, 332(2), 7-23 (2018)
Olivia Jerczynski et al.
PloS one, 11(10), e0163876-e0163876 (2016-10-04)
Dicer1 is an endoribonuclease involved in the biogenesis of functional molecules such as microRNAs (miRNAs) and endogenous small interfering RNAs (endo-siRNAs). These small non-coding RNAs are important regulators of post-transcriptional gene expression and participate in the control of male fertility.
Matthew L Tomlinson et al.
Frontiers in nutrition, 4, 61-61 (2018-01-13)
Flavonoids are a diverse group of plant secondary metabolites, known to reduce inflammatory bowel disease symptoms. How they achieve this is largely unknown. Our study focuses on the gut epithelium as it receives high topological doses of dietary constituents, maintains
Ingunn M Stromnes et al.
Cancer immunology research, 5(11), 978-991 (2017-10-27)
Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy resistant to most therapies, including immune checkpoint blockade. To elucidate mechanisms of immunotherapy resistance, we assessed immune parameters in resected human PDA. We demonstrate significant interpatient variability in T-cell number, localization, and

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