추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
색상
white
mp
161.8-163 °C
solubility
DMSO: 13 mg/mL
저장 온도
2-8°C
SMILES string
CCCN1C(=O)C(C)=Cn2nc(N)nc12
InChI
1S/C9H13N5O/c1-3-4-13-7(15)6(2)5-14-9(13)11-8(10)12-14/h5H,3-4H2,1-2H3,(H2,10,12)
InChI key
UQDVRVNMIJAGRK-UHFFFAOYSA-N
생화학적/생리학적 작용
Phosphodiesterase IV (PDE 4) inhibitor
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
J Abrahamsen et al.
Pharmacology & toxicology, 76(3), 185-189 (1995-03-01)
The possible involvement of cyclic AMP in the stimulation-evoked 3H-overflow from rabbit isolated ear artery preloaded with 3H-noradrenaline was studied. Cyclic AMP (10(-5)-3 x 10(-4)M), 8-bromo-cyclic AMP (3 x 10(-4)M) and adenosine (10(-5)-3 x 10(-4)M) enhanced stimulation-evoked 3H-overflow. Dibutyryl-cyclic AMP
M D Houslay
Cellular signalling, 2(1), 85-98 (1990-01-01)
Using experimentally derived data for the activities and kinetic constants of hepatocyte cyclic AMP phosphodiesterase isoenzymes together with the derived changes in adenylate cyclase activity, due to stimulation and subsequent desensitization by glucagon, a computer model was established to simulate
Z Merican et al.
Clinical and experimental pharmacology & physiology, 10(1), 35-44 (1983-01-01)
1. Cyclic AMP and cyclic GMP levels were determined in bovine splenic nerve segments in the absence and presence of (+/-)-isoprenaline, (-)-phenylephrine, clonidine and ICI 63 197 (a phosphodiesterase inhibitor). The chosen concentrations of adrenoceptor agonists were those which are
Z Merican et al.
Clinical and experimental pharmacology & physiology, 8(1), 57-66 (1981-01-01)
1. Cyclic AMP levels have been determined in the soleus muscles of anaesthetized cats in the absence of drugs, and during depression of incomplete tetanic contractions produced by (-)-isoprenaline, ICI 63,197 (a phosphodiesterase inhibitor) or levodopa. 2. Cyclic AMP levels
M R Mustafa et al.
European journal of pharmacology, 148(2), 171-177 (1988-03-29)
The effects of single and chronic doses of rolipram on the sensitivity of alpha 2-adrenoceptors have been compared with the phosphodiesterase inhibitors, isobutylmethylxanthine (IBMX) and ICI 63,197, and the antidepressant, desipramine. While pretreatment with a single dose of rolipram, ICI
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