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Merck
모든 사진(2)

문서

RAB0365

Sigma-Aldrich

Human MMP-2 ELISA Kit

for serum, plasma, cell culture supernatant

동의어(들):

MMP-2, Matrix metalloproteinase-2

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About This Item

UNSPSC 코드:
41116158
NACRES:
NA.32

종 반응성

human

포장

kit of 96 wells (12 strips x 8 wells)

기술

ELISA: suitable
capture ELISA: suitable

입력

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3,500 pg/mL
standard curve range: 3.3-800 ng/mL

검출 방법

colorimetric

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... MMP2(4313)

일반 설명

The Human MMP-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-2 in serum, plasma, cell culture supernatants and urine.

면역원

Recombinant Human MMP2

애플리케이션

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human MMP-2 ELISA kit has been used for the determination of MMP-2 in serum samples and cell supernatant.
Human MMP-2 ELISA Kit has been used in ELISA (enzyme-linked immunosorbent assay).

생화학적/생리학적 작용

Matrix metalloproteinases (MMPs) enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, which has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. High levels of MMP-2 are observed in the acute phase of transverse myelitis. It is upregulated in colorectal carcinoma and is associated with poor survival outcome. MMP-2 gene haplotypes are also linked with risk of thoracic aortic dissection, a cardiovascular disorder with high death rate.

기타 정보

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

키트 구성품 역시 별도로 이용 가능함

제품 번호
설명
SDS

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

픽토그램

Corrosion

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Met. Corr. 1

Storage Class Code

8B - Non-combustible corrosive hazardous materials

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Matrix metalloproteinases: role in skeletal development and growth plate disorders.
Malemud CJ
Frontiers in Bioscience, 11, 1702-1715 (2006)
IL-33 enhances glioma cell migration and invasion by upregulation of MMP2 and MMP9 via the ST2-NF-?B pathway.
Zhang JF
Oncology Reports, 38, 2033-2033 (2017)
Active matrix metalloprotease-9 is associated with the collagen capsule surrounding the Madurella mycetomatis grain in mycetoma.
Geneugelijk K
PLoS Neglected Tropical Diseases, 8, e2754-e2754 (2014)
MMP-2 functions as an early response protein in ovarian cancer metastasis.
Kenny HA, et. al.
Cell Cycle, 8, 683-688 (2009)
High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma.
Salem N
Future Oncology, 12, 323-331 (2016)

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