S8689

Fas Ligand, soluble human

recombinant, expressed in HEK 293 cells, lyophilized powder

• 동의어(들): SuperFas Ligand^™
• MDL number: MFCD01092558
• UNSPSC 코드: 12352202
• NACRES: NA.56

속성

• 생물학적 소스: human
• Quality Level: 200
• 재조합: expressed in HEK 293 cells
• 분석: ≥95% (SDS-GE)
• 양식: lyophilized powder
• 분자량: 32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions); 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)
• 기술: ligand binding assay: suitable
• UniProt 수납 번호: P48023
• 저장 온도: −20°C
• 유전자 정보: human ... FASLG(356)

설명

애플리케이션

ED₅₀ = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFas Ligand^™ recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.

생화학적/생리학적 작용

Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation. [1]

Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).

법적 정보

SuperFas Ligand is a trademark of Alexis Biochemicals Corp.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable