추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 67 kDa
종 반응성
rat, mouse, human
농도
~1 mg/mL
기술
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... NFE2L2(4780)
관련 카테고리
일반 설명
Anti-NRF2 Antibody detects endogenous levels of total NRF2 protein.
NRF2 (nuclear factor, erythroid 2 like 2) gene is mapped to human chromosome 2q31.2. The encoded protein is localized to dendritic cells. It belongs to the cap ′n′ collar (CNC) family of transcription factors.
면역원
The antiserum was produced against synthesized peptide derived from human Nrf2.
Immunogen Range: 556-605
Immunogen Range: 556-605
애플리케이션
Anti-NRF2, C-Terminal antibody produced in rabbit has been used in western blotting analysis.
생화학적/생리학적 작용
Nrf2 (nuclear factor, erythroid 2 like 2) is involved in the regulation of anti-oxidative and anti-inflammatory response. The protein encoded is a transcription factor that binds to the antioxidant response element of the target gene. In response to oxidative stress, Nrf2 upregulates the enzymes associated with detoxification, anti-inflammation, cytoprotection and antioxidative pathways. Nrf2 affects glucose metabolism and ROS (reactive oxygen species) homeostasis in cancer cells by regulating the pentose phosphate pathway. Thus, Nrf2 is known to contribute to the development of cancer by promoting cell proliferation.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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