제품 이름
Monoclonal Anti-OVA antibody produced in mouse, clone 3G2E1D9, ascites fluid
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
3G2E1D9, monoclonal
technique(s)
direct ELISA: 1:10,000
western blot: 1:500-1:2,000
isotype
IgG1
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Biochem/physiol Actions
Ovalbumin (OVA) peptide 323-339 mediates 25-35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation. It is extensively used in allergy research.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes.
Immunogen
Ovalbumin
Mouse monoclonal antibody raised against OVA
Mouse monoclonal antibody raised against OVA
Physical form
Ascitic fluid containing 0.03% sodium azide.
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저장 등급
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Keigo Kondou et al.
Journal of biological engineering, 13, 77-77 (2019-10-28)
The baculovirus (BV) Autographa californica multiple nuclear polyhedrosis virus has been used in numerous protein expression systems because of its ability to infect insect cells and serves as a useful vaccination vector with several benefits, such as its low clinical
Comparison between ovalbumin and ovalbumin peptide 323-339 responses in allergic mice: humoral and cellular aspects.
Sun LZ
Scandinavian Journal of Immunology, 71(5), 329-335 (2010)
Ingrid S Zeelenberg et al.
Cancer research, 68(4), 1228-1235 (2008-02-19)
Expression of non-self antigens by tumors can induce activation of T cells in vivo, although this activation can lead to either immunity or tolerance. CD8+ T-cell activation can be direct (if the tumor expresses MHC class I molecules) or indirect
Tian-Yu Song et al.
Nature communications, 12(1), 7003-7003 (2021-12-03)
Cancer cells acquire genetic heterogeneity to escape from immune surveillance during tumor evolution, but a systematic approach to distinguish driver from passenger mutations is lacking. Here we investigate the impact of different immune pressure on tumor clonal dynamics and immune
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