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Merck
모든 사진(1)

주요 문서

SML0503

Sigma-Aldrich

9(S)-HODE

≥98% (HPLC)

동의어(들):

9S-Hydroxy-10E,12Z-octadecadienoic acid

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About This Item

실험식(Hill 표기법):
C18H32O3
CAS Number:
Molecular Weight:
296.44
EC Number:
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.77

가격 및 재고 정보를 현재 이용할 수 없음

Quality Level

분석

≥98% (HPLC)

양식

solution

농도

1 mg/mL in ethanol

색상

colorless to light yellow

배송 상태

wet ice

저장 온도

−20°C

SMILES string

CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O

InChI

1S/C18H32O3/c1-2-3-4-5-6-8-11-14-17(19)15-12-9-7-10-13-16-18(20)21/h6,8,11,14,17,19H,2-5,7,9-10,12-13,15-16H2,1H3,(H,20,21)/b8-6-,14-11+/t17-/m1/s1

InChI key

NPDSHTNEKLQQIJ-UINYOVNOSA-N

생화학적/생리학적 작용

9(S)-HODE is a pro-inflammatory linoleic acid lipoxygenation product.
9(S)-HODE is produced by the lipoxygenation of linoleic acid. It is a major component of plasma oxidized low-density lipoprotein. 9-HODE has been shown to stimulate cell proliferation and and extracellular matrix synthesis in human mesangial cells via PPARgamma. Pro-inflammatory effects of 9-HODE, acting through the receptor GPR132, can contribute to atherosclerosis progression. 9-HODE has also been shown to activate spinal TRPV1, leading to inflammatory hyperalgesia.

픽토그램

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신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

57.2 °F - closed cup

Flash Point (°C)

14.0 °C - closed cup


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시험 성적서(COA)

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