추천 제품
product name
Zaragozic acid A trisodium salt, ≥95% (HPLC), microbial
생물학적 소스
microbial
Quality Level
분석
≥95% (HPLC)
형태
lyophilized powder
solubility
DMSO: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
배송 상태
wet ice
저장 온도
−20°C
애플리케이션
Zaragozic acid A trisodium salt has been used as:
- a component of serum-free medium for human embryonic kidney cells in a wound scratch assay to test its effect on wound healing
- a farnesyl-diphosphate farnesyltransferase 1 (FDFT1) or squalene synthase inhibitor in stromal cells
- a cholesterol synthesis inhibitor in T cells
생화학적/생리학적 작용
Potent inhibitor, in vivo and in vitro, of mammalian, fungal and Saccharomyces cervisiae squalene synthase. Squalene synthase is the first committed enzyme in sterol synthesis, catalyzing the reductive condensation of farnesyl pyrophosphate to form squalene. As a squalene synthase inhibitor, zaragozic acid produces lower plasma cholesterol levels in primates. Treatment of rats with zaragozic acid A caused an increase in hepatic low density lipoprotein (LDL) receptor mRNA levels.
법적 정보
Manufactured and sold under a restricted license from Merck & Co., Inc., Kenilworth, NJ, U.S.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
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문서
지질 신호전달 연구를 위한 생체 활성 저분자
Discover Bioactive Small Molecules for Lipid Signaling Research
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