390062

Thiazole Orange

Dye content ~90 %

• Synonym(s): 1-Methyl-4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]quinolinium p-tosylate
• สูตรเอมพิริกัล (Hill Notation): C₂₆H₂₄N₂O₃S₂
• CASE番号: 107091-89-4
• น้ำหนักโมเลกุล: 476.61
• NACRES: NA.47
• PubChem Substance ID: 24864313
• UNSPSC Code: 12171500
• MDL number: MFCD00192499

คุณสมบัติ

• form: powder
• Quality Segment: 200
• composition: Dye content, ~90%
• technique(s): titration: suitable
• mp: 270 °C (dec.) (lit.)
• λmax: 512 nm
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: Cc1ccc(cc1)S([O-])(=O)=O.CN2C(\Sc3ccccc23)=C\c4cc[n+](C)c5ccccc45
• InChI: 1S/C19H17N2S.C7H8O3S/c1-20-12-11-14(15-7-3-4-8-16(15)20)13-19-21(2)17-9-5-6-10-18(17)22-19;1-6-2-4-7(5-3-6)11(8,9)10/h3-13H,1-2H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
• InChI key: ACOJCCLIDPZYJC-UHFFFAOYSA-M

คำอธิบาย

General description

Thiazole Orange can be tethered with peptide nucleic acid for the detection of target nucleic acid in homogeneous solution. It is a dye with, both predicted physical characteristics and the biological staining characteristics of a good reticulocyte dye, hence it is considered as a dye for reticulocyte analysis. It has massive fluorescence enhancement and high quantum yield upon binding to nucleic acids, particularly RNA. It is non precipitating and can permeates through live cell membranes.

Application

Thiazole orange has been used for the staining and thereby quantification of reticulocytes.

ข้อมูลความปลอดภัย

• สัญลักษณ์รูปภาพ: GHS07
• คำเตือน: Warning
• รหัสอันตราย: H315,H319,H335
• คำเตือน: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• อวัยวะเป้าหมาย: Respiratory system
• คลาสการจัดเก็บ: 11 - Combustible Solids
• มีอะไรเกิดขึ้น?: WGK 3
• จุดติดไฟ (°F): Not applicable
• จุดวาบไฟ (°C): Not applicable
• อุปกรณ์ป้องกันส่วนบุคคล (PPE): dust mask type N95 (US), Eyeshields, Gloves