MilliporeSigma

AVP

arginine vasopressin

Synonyms:
ADH, ARVP, AVP-NPII, AVRP, VP
Species:
UniProtKB ID:
Gene ID:
  • Human(551) Summary: This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). [provided by RefSeq, Mar 2010]
  • Mouse(11998) arginine vasopressin
  • Rat(24221) arginine vasopressin
  • cow(280728) arginine vasopressin
  • domestic cat(101096305) arginine vasopressin
  • dog(403579) arginine vasopressin
  • chicken(396101) arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal)
  • Zebrafish(352922) arginine vasopressin
  • domestic guinea pig(100716009) arginine vasopressin
  • sheep(443477) arginine vasopressin

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Copeptin antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Neurophysin 2/NP-AVP Antibody, clone PS 45, clone PS 45, from mouse,
Species Reactivity
bovine, frog, human, mouse, rat
Application
ELISA
electron microscopy

immunohistochemistry

immunoprecipitation (IP)

radioimmunoassay

western blot
ANTI-AVP (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Vasopressin Rabbit pAb, lyophilized, Calbiochem®,
Species Reactivity
rat
Application
Anti-Neurophysin 2/NP-AVP Antibody, clone PS 41, clone PS 41, from mouse,
Species Reactivity
rat
Application
ELISA
electron microscopy

immunohistochemistry

immunoprecipitation (IP)

radioimmunoassay

western blot

Proteins

Product Number
Description
Species
[Arg8]-Vasotocin acetate salt, ≥97% (HPLC),
Species
human
[Arg8]-Vasopressin solution, Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl,
Species
human
[Lys8]-Vasopressin, ≥98% (HPLC),
Species
human
[Arg8]-Vasopressin acetate salt, ≥95% (HPLC),
Species
human