MilliporeSigma
All Photos(1)

V0377

Sigma-Aldrich

[Arg8]-Vasopressin solution

Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl

Sign Into View Organizational & Contract Pricing

Select a Size

Synonym(s):
β-Hypophamine, AVP, Antidiuretic hormone, Arginine vasopressin
Empirical Formula (Hill Notation):
C46H65N15O12S2
CAS Number:
Molecular Weight:
1084.23
MDL number:
PubChem Substance ID:
NACRES:
NA.32

biological source

synthetic (organic)

Quality Level

sterility

non-sterile

type

Grade VI (synthetic)

form

liquid

contains

0.4% 4-chlorobutanol as preservative

concentration

~100 IU/mL in 0.9% NaCl

pH

~3.5

UniProt accession no.

shipped in

ambient

storage temp.

2-8°C

SMILES string

NC1CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(Cc2ccccc2)NC(=O)C(Cc3ccc(O)cc3)NC1=O)C(=O)N4CCCC4C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O

InChI

1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)

InChI key

KBZOIRJILGZLEJ-UHFFFAOYSA-N

Gene Information

human ... AVP(551)

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
V9879V6879O4375
[Lys8]-Vasopressin ≥98% (HPLC)

Sigma-Aldrich

V6879

[Lys8]-Vasopressin

Oxytocin lyophilized powder, ~15 IU/mg solid (Prepared from synthetic oxytocin)

Sigma-Aldrich

O4375

Oxytocin

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

form

liquid

form

powder

form

powder

form

lyophilized powder

concentration

~100 IU/mL in 0.9% NaCl

concentration

-

concentration

-

concentration

-

pH

~3.5

pH

-

pH

-

pH

-

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

Amino Acid Sequence

Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]

Application

[Arg8]-Vasopressin solution was used as an antigen for preparing preadsorbed antisera for immunocytochemistry. The product was used in L6 cell culture of the C5 subclone for differentiation studies.

Biochem/physiol Actions

Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg8-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).
[Arg8]-Vasopressin solution also known as Antidiuretic hormone, Arginine vasopressin or beta-Hypophamine is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. It stimulates three acid-base transporters and hence increases the capability of the cell to regulate pH.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 5

1 of 5

Oxytocin lyophilized powder, ~15 IU/mg solid (Prepared from synthetic oxytocin)

Sigma-Aldrich

O4375

Oxytocin

Oxytocin United States Pharmacopeia (USP) Reference Standard

USP

1491300

Oxytocin

Aldosterone ≥95% (HPLC)

Sigma-Aldrich

A9477

Aldosterone

Angiotensin II human ≥93% (HPLC), powder

Sigma-Aldrich

A9525

Angiotensin II human

J J McDonnell et al.
The Anatomical record, 240(4), 528-536 (1994-12-01)
Beta-endorphin and oxytocin immunocytochemical localization were examined in the neurointermediate lobe (lobus nervosus and pars intermedia) of the bovine hypophysis in order to describe the anatomical distribution of these two neurointermediate lobe hormones. Twenty-seven bovine hypophyses were collected from slaughterhouse
Natalie Yuen et al.
American journal of physiology. Cell physiology, 306(10), C931-C942 (2014-03-22)
Brain edema forms rapidly in the early hours of ischemic stroke by increased secretion of Na, Cl, and water into the brain across an intact blood-brain barrier (BBB), together with swelling of astrocytes as they take up the ions and
Vasopressin antagonists for patients with acute heart failure: interpreting new clinical and translational data.
A M Feldman et al.
Clinical pharmacology and therapeutics, 95(4), 373-375 (2013-12-19)
Daniel J van Wamelen et al.
Sleep, 36(1), 117-125 (2013-01-05)
To study whether sleep and circadian rhythm disturbances in patients with Huntington's disease (HD) arise from dysfunction of the body's master clock, the hypothalamic suprachiasmatic nucleus. Postmortem cohort study. Eight patients with HD and eight control subjects matched for sex
Vanessa Vezzi et al.
Scientific reports, 10(1), 9111-9111 (2020-06-06)
Vasopressin receptor 2 (V2R) mutations causing the nephrogenic syndrome of inappropriate antidiuresis (NSIAD) can generate two constitutively active receptor phenotypes. One type results from residue substitutions in several V2R domains and is sensitive to vaptan inverse agonists. The other is

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service