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Merck

AVP

arginine vasopressin

Synonymes:
ADH, ARVP, AVP-NPII, AVRP, VP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(551) Summary: This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). [provided by RefSeq, Mar 2010]
  • Mouse(11998) arginine vasopressin
  • Rat(24221) arginine vasopressin
  • cow(280728) arginine vasopressin
  • domestic cat(101096305) arginine vasopressin
  • dog(403579) arginine vasopressin
  • chicken(396101) arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal)
  • Zebrafish(352922) arginine vasopressin
  • domestic guinea pig(100716009) arginine vasopressin
  • sheep(443477) arginine vasopressin

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Vasopressin Antibody, serum, Chemicon®,
Espèces réactives
human, mouse, rabbit, rat, sheep
Application
immunocytochemistry
immunohistochemistry

radioimmunoassay

western blot
Anti-Vasopressin Rabbit pAb, lyophilized, Calbiochem®,
Espèces réactives
rat
Application
Anticorps anti-neurophysine 2/NP-AVP, clone PS 41, clone PS 41, from mouse,
Espèces réactives
rat
Application
ELISA
electron microscopy

immunohistochemistry

immunoprecipitation (IP)

radioimmunoassay

western blot
Anti-Neurophysin 2/NP-AVP Antibody, clone PS 45, clone PS 45, from mouse,
Espèces réactives
bovine, frog, human, mouse, rat
Application
ELISA
electron microscopy

immunohistochemistry

immunoprecipitation (IP)

radioimmunoassay

western blot
Anti-Copeptin antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot

Proteins

Numéro du produit
Description
Espèce(s)
[Arg8]-Vasopressin solution, Grade VI (synthetic), ~100 IU/mL in 0.9% NaCl,
Espèce(s)
human
[Lys8]-Vasopressin, ≥98% (HPLC),
Espèce(s)
human
[Arg8]-Vasotocin acetate salt, ≥97% (HPLC),
Espèce(s)
human
[Arg8]-Vasopressin acetate salt, ≥95% (HPLC),
Espèce(s)
human