MilliporeSigma

CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

Synonyms:
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Species:
UniProtKB ID:
Gene ID:
  • Human(1140) Summary: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(11443) cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
  • Rat(24261) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic cat(101097433) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Domestic Rabbit(100357163) cholinergic receptor, nicotinic, beta 1 (muscle)
  • sheep(101121614) cholinergic receptor, nicotinic, beta 1 (muscle)
  • naked mole-rat(101723288) cholinergic receptor, nicotinic, beta 1 (muscle)
  • domestic guinea pig(100714100) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Zebrafish(100006941) cholinergic receptor, nicotinic, beta 1 (muscle)
  • dog(489473) cholinergic receptor, nicotinic, beta 1 (muscle)
  • cow(282179) cholinergic receptor, nicotinic, beta 1 (muscle)
  • Horse(100072990) cholinergic receptor, nicotinic, beta 1 (muscle)

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Small Molecule - Agonist

Product Number
Description
Species
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat
Decamethonium bromide, crystalline,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
Cisatracurium besilate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Vecuronium for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Atracurium for impurity F identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Atracurium besylate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Cisatracurium for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Blocker

Product Number
Description
Species
Tetraethylammonium chloride, ≥98% (titration),
Species
human
Hexamethonium chloride, solid (hygroscopic),
Species
human
Hexamethonium bromide, ,
Species
human
Kynurenic acid, ≥98%,
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHRNB1,
Species
human
MISSION® esiRNA, targeting mouse Chrnb1,
Species
mouse