P1918

Pancuronium bromide

• Synonym(s): 1,1′-[(2β,3α,5α,16β,17β)-3,17-bis(Acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide
• Empirical Formula (Hill Notation): C₃₅H₆₀Br₂N₂O₄
• CAS Number: 15500-66-0
• Molecular Weight: 732.67
• Beilstein/REAXYS Number: 4226892
• EC Number: 239-532-5
• MDL number: MFCD00079223
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278623
• NACRES: NA.77

Properties

• form: powder
• originator: Organon
• SMILES string: [Br-].[Br-].[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@@H](OC(C)=O)[C@H](C[C@@]34[H])[N+]5(C)CCCCC5)[C@@]1(C)C[C@@H]([C@H](C2)OC(C)=O)[N+]6(C)CCCCC6
• InChI: 1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1
• InChI key: NPIJXCQZLFKBMV-YTGGZNJNSA-L
• Gene Information: human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

Description

General description

Pancuronium bromide is a biquarternary amino steroid. It blocks muscarinic acetylcholine receptors (M₂) in the heart. Pancuronium has vagolytic and sympathomimetic properties. It is associated with tachycardia and hypertension.

Application

Pancuronium Bromide has been used as an analgesic in various experiments.

Biochem/physiol Actions

Aminosteroidal neuromuscular blocking agent; skeletal muscle relaxant

Features and Benefits

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This compound was developed by Organon. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves