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5.05226

Sigma-Aldrich

Pancuronium Dibromide

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Synonym(s):
Pancuronium Dibromide, 1,1ʹ-(3α,17β-Dihydroxy-2α,5β-androstan-2-β,16β-ylene) bis[1-methylpiperidinium] diacetate dibromide, Nicotinic Acetylchorine Receptor Antagonist, Pancuronium Dibromide, nAChR Antagonist, Pancuronium Dibromide
Empirical Formula (Hill Notation):
C35H60N2O4 · Br2
CAS Number:
Molecular Weight:
732.67
MDL number:

assay

≥98% (NMR)

Quality Level

form

solid

potency

5.5 nM IC50

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

water: 100 mM

storage temp.

2-8°C

InChI

1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1

InChI key

NPIJXCQZLFKBMV-YTGGZNJNSA-L

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This Item
P1918BP276Y0000577
vibrant-m

5.05226

Pancuronium Dibromide

vibrant-m

P1918

Pancuronium bromide

vibrant-m

BP276

Pancuronium bromide

form

solid

form

powder

form

-

form

-

assay

≥98% (NMR)

assay

-

assay

-

assay

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

BP

manufacturer/tradename

EDQM

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

-

storage condition

-

General description

A highly potent competitive antagonist selective for nAChRs (IC50 = 5.5 nM). A very potent non-depolarizing skeletal muscle relaxant but no sedative or analgesic effects.

Biochem/physiol Actions

Primary Target
nAChR

Warning

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Lowenick et al., 2001. Eur. J. Pharmacol.413, 31.

Melnikov, L., et al., 1999. Gen Pharmacol.33, 313.

Maestrone, E., et al., 1994. Br. J. Pharmacol.111, 283.

Fryer, D., et al., 1987. Naunyn Schmiedebergs Arch. Pharmacol.335, 367.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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