CHRNG
cholinergic receptor, nicotinic, gamma (muscle)
Synonyms:
ACHRG
Species:
Human CHRNG (1146), Mouse Chrng (11449), Rat Chrng (25753), cow CHRNG (281689), Zebrafish chrng (325080), dog CHRNG (486163), domestic cat CHRNG (101098733), chicken CHRNG (429151), naked mole-rat Chrng (101706620), sheep CHRNG (101102965)
UniProtKB ID:
Gene ID:
- Human(1146) Summary: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[provided by RefSeq, Sep 2009]
- Mouse(11449) cholinergic receptor, nicotinic, gamma polypeptide
- Rat(25753) cholinergic receptor, nicotinic, gamma (muscle)
- cow(281689) cholinergic receptor, nicotinic, gamma (muscle)
- Zebrafish(325080) cholinergic receptor, nicotinic, gamma
- dog(486163) cholinergic receptor, nicotinic, gamma (muscle)
- domestic cat(101098733) cholinergic receptor, nicotinic, gamma (muscle)
- chicken(429151) cholinergic receptor, nicotinic, gamma
- naked mole-rat(101706620) cholinergic receptor, nicotinic, gamma (muscle)
- sheep(101102965) cholinergic receptor, nicotinic, gamma (muscle)
- domestic guinea pig(100733530) cholinergic receptor, nicotinic, gamma (muscle)
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Small Molecule - Agonist
Product Number
Description
Species
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CHRNG, N-terminal region antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, human, rabbit
Application
western blot