MilliporeSigma

GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2561) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008]
  • Mouse(14401) gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
  • Rat(25451) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • sheep(100913155) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • domestic guinea pig(100720162) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • naked mole-rat(101721168) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Zebrafish(336252) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • domestic cat(101094237) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • cow(540657) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Domestic Rabbit(100356357) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Horse(100059608) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • chicken(414890) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • dog(489146) gamma-aminobutyric acid (GABA) A receptor, beta 2

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Small Molecule - Agonist

Product Number
Description
Species
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Species
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Species
human
Piperidine-4-sulfonic acid, ,
Species
human
Isoguvacine hydrochloride, solid,
Species
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Species
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Species
human
5α-Pregnan-3α-ol-11,20-dione, powder, ≥98% (TLC),
Species
human
trans-Dehydroandrosterone, ≥99%,
Species
human, rat
Oxazepam, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Picrotoxin, powder,
Species
human
Pregnenolone sulfate sodium salt, ,
Species
human
SR-95531, ≥98% (HPLC), powder,
Species
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Species
human
trans-Dehydroandrosterone, ≥99%,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17, clone BD17, Chemicon®, from mouse,
Species Reactivity
bovine, feline, human, monkey, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-GABA A Receptor beta 2 (GABRB2) Antibody, clone 6G9O8, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-GABA A Receptor β2 Antibody, cytoplasmic loop, Chemicon®, from rabbit,
Species Reactivity
bovine, human, mouse, rat
Application
immunoprecipitation (IP)
western blot
Anti-GABRB2 Antibody, clone BD17 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, feline, human, monkey, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-GABRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
NO-711 hydrochloride, ≥98% (HPLC),
Species
human
(±)-Vigabatrin, ,
Species
human
2,6-Diisopropylphenol, 97%,
Species
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Topiramate, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Etomidate, >98% (HPLC), powder,
Species
human
Flumazenil, >99% (HPLC), solid,
Species
rat, human
Carbamazepine, powder,
Species
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GABRB2,
Species
human
MISSION® esiRNA, targeting mouse Gabrb2,
Species
mouse