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HDAC2

histone deacetylase 2

Synonyms:
HD2, RPD3, YAF1
Species:
UniProtKB ID:
Gene ID:
  • Human(3066) Summary: This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
  • Mouse(15182) histone deacetylase 2
  • Rat(84577) histone deacetylase 2
  • chicken(395635) histone deacetylase 2
  • domestic cat(101088165) histone deacetylase 2
  • dog(475035) histone deacetylase 2
  • sheep(101107708) histone deacetylase 2
  • cow(407223) histone deacetylase 2
  • naked mole-rat(101712029) histone deacetylase 2
  • domestic guinea pig(100715675) histone deacetylase 2

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
ChIPAb+ HDAC2 - ChIP Validated Antibody and Primer Set, from mouse,
Species Reactivity
bovine, hamster, human, mouse, rat
Application
ChIP
western blot
Anti-HDAC2 Antibody, clone 3F3, clone 3F3, Upstate®, from mouse,
Species Reactivity
bovine, hamster, human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-HDAC2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-HDAC2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
Anti-phospho-HDAC2 (pSer394) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

Proteins

Product Number
Description
Species
HDAC2 FLAG tag human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
Species
human
HDAC2, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
HDAC 2 His tag human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Hdac2,
Species
mouse
MISSION® esiRNA, targeting human HDAC2,
Species
human