KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
Synonyms:
BFNC2, EBN2, KV7.3
Species:
Human KCNQ3 (3786), Mouse Kcnq3 (110862), Rat Kcnq3 (29682), chicken KCNQ3 (420325), naked mole-rat Kcnq3 (101726081), domestic guinea pig Kcnq3 (100722068), sheep KCNQ3 (101120673), domestic cat KCNQ3 (101093496), Horse KCNQ3 (100057886), cow KCNQ3 (281884) ...More
UniProtKB ID:
Gene ID:
- Human(3786) Summary: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found. [provided by RefSeq, Mar 2011]
- Mouse(110862) potassium voltage-gated channel, subfamily Q, member 3
- Rat(29682) potassium voltage-gated channel, KQT-like subfamily, member 3
- chicken(420325) potassium voltage-gated channel, KQT-like subfamily, member 3
- naked mole-rat(101726081) potassium voltage-gated channel, KQT-like subfamily, member 3
- domestic guinea pig(100722068) potassium voltage-gated channel, KQT-like subfamily, member 3
- sheep(101120673) potassium voltage-gated channel, KQT-like subfamily, member 3
- domestic cat(101093496) potassium voltage-gated channel, KQT-like subfamily, member 3
- Horse(100057886) potassium voltage-gated channel, KQT-like subfamily, member 3
- cow(281884) potassium voltage-gated channel, KQT-like subfamily, member 3
- dog(475103) potassium voltage-gated channel, KQT-like subfamily, member 3
- Zebrafish(799747) potassium voltage-gated channel, KQT-like subfamily, member 3
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Small Molecule - Activator
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Description
Species
Antibodies
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Description
Species Reactivity
Application
Anti-KCNQ3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Small Molecule - Blocker
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Description
Species
esiRNA
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Description
Species