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MYC

v-myc avian myelocytomatosis viral oncogene homolog

Synonyms:
MRTL, MYCC, bHLHe39, c-Myc
Species:
UniProtKB ID:
Gene ID:
  • Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17869) myelocytomatosis oncogene
  • Rat(24577) myelocytomatosis oncogene
  • chicken(420332) v-myc myelocytomatosis viral oncogene homolog
  • dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
  • cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
  • sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)
  • Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
  • domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)

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ELISA

Product Number
Description
Species
Human c-Myc ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MYC antibody produced in mouse, clone 1G7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-MYC-FITC , (C-terminal) antibody produced in mouse, clone 9E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
fusion proteins in all species, human
Application
flow cytometry
Anti-MyC (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, human, mouse, rat
Application
western blot
Anti-c-Myc−Peroxidase antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-c-Myc (ab1) antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

Proteins

Product Number
Description
Species
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Myc,
Species
mouse
MISSION® esiRNA, targeting human MYC,
Species
human