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POLD1

polymerase (DNA directed), delta 1, catalytic subunit

Synonyms:
CDC2, CRCS10, MDPL, POLD
Species:
UniProtKB ID:
Gene ID:
  • Human(5424) Summary: This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]
  • Mouse(18971) polymerase (DNA directed), delta 1, catalytic subunit
  • Rat(59294) polymerase (DNA directed), delta 1, catalytic subunit
  • naked mole-rat(101699680) polymerase (DNA directed), delta 1, catalytic subunit
  • domestic cat(101086519) polymerase (DNA directed), delta 1, catalytic subunit
  • domestic guinea pig(100719673) polymerase (DNA directed), delta 1, catalytic subunit
  • Horse(100052455) polymerase (DNA directed), delta 1, catalytic subunit
  • Zebrafish(556456) polymerase (DNA directed), delta 1, catalytic subunit
  • cow(281990) polymerase (DNA directed), delta 1, catalytic subunit
  • sheep(101117012) polymerase (DNA directed), delta 1, catalytic subunit
  • dog(610047) polymerase (DNA directed), delta 1, catalytic subunit

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DNA polymerase δ p125 antibody, Rat monoclonal, clone PDG 5G1, purified from hybridoma cell culture,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-POLD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-POLD1 antibody produced in mouse, ,
Species Reactivity
human, mouse
Application
western blot
Anti-POLD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-POLD1 Antibody, clone 4B6I3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Aphidicolin from Nigrospora sphaerica, ≥98% (HPLC), powder,
Species
human
Sodium phosphonoformate tribasic hexahydrate, ,
Species
rat, human
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Species
human
Cytosine β-D-arabinofuranoside hydrochloride, crystalline,
Species
human
Cytarabine, British Pharmacopoeia (BP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human POLD1,
Species
human
MISSION® esiRNA, targeting mouse Pold1,
Species
mouse