MilliporeSigma

PPP1CA

protein phosphatase 1, catalytic subunit, alpha isozyme

Synonyms:
PP-1A, PP1A, PP1alpha, PPP1A
Species:
UniProtKB ID:
Gene ID:
  • Human(5499) Summary: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19045) protein phosphatase 1, catalytic subunit, alpha isoform
  • Rat(24668) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic guinea pig(100721697) protein phosphatase 1, catalytic subunit, alpha isozyme
  • sheep(101119264) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Horse(100059233) protein phosphatase 1, catalytic subunit, alpha isozyme
  • dog(403609) protein phosphatase 1, catalytic subunit, alpha isozyme
  • naked mole-rat(101705408) protein phosphatase 1, catalytic subunit, alpha isozyme
  • domestic cat(101080405) protein phosphatase 1, catalytic subunit, alpha isozyme
  • cow(516175) protein phosphatase 1, catalytic subunit, alpha isozyme
  • Domestic Rabbit(100009298) protein phosphatase 1, catalytic subunit, alpha isozyme

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Antibodies

Product Number
Description
Species Reactivity
Application
Rabbit anti-PPP1CA Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Monoclonal Anti-PPP1CA antibody produced in mouse, clone 5E9, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-ZAP-70 Antibody, clone 1E7.2, clone 1E7.2, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Phospho-PPP1CA-T320 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-PPP1CA Antibody, clone 5E9, ascites fluid, clone 5E9, from mouse,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
PP1α Protein, 10 µg, Recombinant, full length, human PP1α, for use in Phosphatase Assays.,
Species
human
PP1A, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Protein Phosphatase-1 Catalytic Subunit, α-Isoform from rabbit, 5,000-15,000 units/mg protein, recombinant, expressed in E. coli, lyophilized powder,
Species
domestic rabbit

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ppp1ca,
Species
mouse
MISSION® esiRNA, targeting human PPP1CA,
Species
human