MilliporeSigma

PSMA1

proteasome (prosome, macropain) subunit, alpha type, 1

Synonyms:
HC2, NU, PROS30
Species:
UniProtKB ID:
Gene ID:
  • Human(5682) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
  • Mouse(26440) proteasome (prosome, macropain) subunit, alpha type 1
  • Rat(29668) proteasome (prosome, macropain) subunit, alpha type 1
  • domestic guinea pig(100731270) proteasome (prosome, macropain) subunit, alpha type, 1
  • chicken(395874) proteasome (prosome, macropain) subunit, alpha type, 1
  • naked mole-rat(101724081) proteasome (prosome, macropain) subunit, alpha type, 1
  • cow(515503) proteasome (prosome, macropain) subunit, alpha type, 1
  • domestic cat(101093640) proteasome (prosome, macropain) subunit, alpha type, 1
  • sheep(101118048) proteasome (prosome, macropain) subunit, alpha type, 1
  • Horse(100056224) proteasome (prosome, macropain) subunit, alpha type, 1
  • Zebrafish(445033) proteasome (prosome, macropain) subunit, alpha type, 1
  • dog(476867) proteasome (prosome, macropain) subunit, alpha type, 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PSMA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-PSMA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PSMA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PSMA1 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Calpain Inhibitor I, ≥97% (TLC), powder,
Species
human
MG-132(R), ≥95% (HPLC),
Species
human
Z-Leu-Leu-Leu-al, ≥90% (HPLC),
Species
human
Z-Leu-Leu-Norvalinal, ≥90% (HPLC), powder,
Species
rat, mouse, human

Proteins

Product Number
Description
Species
20S Proteasome Fraction from rabbit, ≥95% (SDS-PAGE), solution,
Species

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PSMA1,
Species
human
MISSION® esiRNA, targeting mouse Psma1,
Species
mouse