MilliporeSigma

S100B

S100 calcium binding protein B

Synonyms:
NEF, S100, S100-B, S100beta
Species:
UniProtKB ID:
Gene ID:
  • Human(6285) Summary: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(20203) S100 protein, beta polypeptide, neural
  • Rat(25742) S100 calcium binding protein B
  • dog(491615) S100 calcium binding protein B
  • domestic cat(101099488) S100 calcium binding protein B
  • cow(525716) S100 calcium binding protein B
  • Zebrafish(436825) S100 calcium binding protein, beta (neural)
  • chicken(424038) S100 calcium binding protein B
  • domestic guinea pig(100726901) S100 calcium binding protein B
  • naked mole-rat(101719562) S100 calcium binding protein B
  • sheep(101113190) S100 calcium binding protein B
  • Domestic Rabbit(100009495) S100 calcium binding protein B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-S-100 (β-Subunit) antibody, Mouse monoclonal, clone SH-B1, purified from hybridoma cell culture,
Species Reactivity
bovine, cat, human, porcine, rabbit, rat
Application
immunohistochemistry
Anti-S100B antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-S100B Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human, mouse, rat, rhesus macaque
Application
immunohistochemistry
western blot
Anti-S100B antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-S100B antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human S100B,
Species
human