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16005

Sigma-Aldrich

Paraformaldehyde

meets analytical specification of DAC, 95.0-100.5%

Synonym(s):

Polyoxymethylene

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About This Item

Linear Formula:
HO(CH2O)nH
CAS Number:
Molecular Weight:
30.03 (as monomer)
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor density

1.03 (vs air)

vapor pressure

<1.45 mmHg ( 25 °C)

assay

95.0-100.5%

form

pellets

autoignition temp.

572 °F

quality

meets analytical specification of DAC

expl. lim.

73 %

technique(s)

NMR: suitable

impurities

residual solvents, in accordance
<0.1% sulfated ash
10 ppm heavy metals (as Pb)

mp

120-170 °C (lit.)

solubility

water: insoluble

density

0.88 g/mL at 25 °C (lit.)

suitability

in accordance for appearance of solution
suitable for acidity or alkalinity (complying)

storage temp.

2-8°C

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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General description

Buffered picric acid-paraformaldehyde fixative is suitable for use in electron microscopy and light-microscopic immunocytochemistry.

Application

Paraformaldehyde was used in the preparation of azomethine ylide, required for the synthesis of amine-modifying single-walled carbon nanotubes. It was also used in the preparation of α-methylenechromanes, α-methylenequinoline and ortho-quinone methides.

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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Sol. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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P Somogyi et al.
Neuroscience, 7(7), 1779-1783 (1982-07-01)
The buffered picric acid paraformaldehyde fixative originally recommended for electronmicroscopy and which has since been used occasionally for light-microscopic immunocytochemistry, has been supplemented with glutaraldehyde and used as primary fixative for the perfusion of rat brains. In the basal ganglia
J Justin Mulvey et al.
International journal of nanomedicine, 9, 4245-4255 (2014-09-18)
We aimed to create a more robust and more accessible standard for amine-modifying single-walled carbon nanotubes (SWCNTs). A 1,3-cycloaddition was developed using an azomethine ylide, generated by reacting paraformaldehyde and a side-chain-Boc (tert-Butyloxycarbonyl)-protected, lysine-derived alpha-amino acid, H-Lys(Boc)-OH, with purified SWCNT
José C J M D S Menezes et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 20(42), 13644-13655 (2014-08-30)
In view of increasing demands for efficient photosensitizers for photodynamic therapy (PDT), we herein report the synthesis and photophysical characterizations of new chlorin e6 trimethyl ester and protoporphyrin IX dimethyl ester dyads as free bases and Zn(II) complexes. The synthesis of these
Ting Yao et al.
FEBS open bio, 6(7), 707-719 (2016-07-12)
Decorin (DCN) is a major member of the small leucine-rich proteoglycan (SLRP) family that is critically involved in tumorigenesis and the development of metastasis of cancers, including glioma. Overexpression of DCN was indicated to suppress glioma cell growth. However, the
Johanna Zemva et al.
Redox biology, 13, 674-686 (2017-08-22)
Energy production is inevitably linked to the generation of toxic metabolites, such as reactive oxygen and carbonyl species, known as major contributors to ageing and degenerative diseases. It remains unclear how cells can adapt to elevated energy flux accompanied by

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