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Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

PEG average Mn 5,000, PLGA average Mn 25,000, lactide:glycolide 50:50

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Synonym(s):
PEG-PLGA, PEG-b-PLGA
Linear Formula:
CH3[C2H4O]nO[(C2H2O2)x(C3H4O2)y]mH
NACRES:
NA.23

form

powder

Quality Level

mol wt

PEG average Mn 5,000
PLGA average Mn 25,000

composition

lactide:glycolide 50:50

storage temp.

2-8°C

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This Item
911410911429911399
storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

mol wt

PEG average Mn 5,000

mol wt

PEG average Mn 5,000 (by NMR), PLGA average Mn 10,000 (by NMR)

mol wt

PEG average Mn 5,000 (by NMR), PLGA average Mn 5,000 (by NMR)

mol wt

PEG average Mn 2,000 (by NMR), PLGA average Mn 10,000 (by NMR)

composition

lactide:glycolide 50:50

composition

-

composition

-

composition

-

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

Application

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs

Features and Benefits

  • Good biocompatibility, low immunogenicity and good degradability.
  • Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

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