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239785

Sigma-Aldrich

Cyclophosphamide Monohydrate

A widely used anti-neoplastic agent that also displays immunosuppressant properties.

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Synonym(s):
Cyclophosphamide Monohydrate, N,N- bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA, N,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA
Empirical Formula (Hill Notation):
C7H15Cl2N2O2P · xH2O
CAS Number:
Molecular Weight:
261.09 (anhydrous basis)
MDL number:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 30 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChI key

PWOQRKCAHTVFLB-UHFFFAOYSA-N

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This Item
C0768PHR1404C7397
Cyclophosphamide Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1404

Cyclophosphamide

form

solid

form

powder

form

-

form

powder

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

storage condition

OK to freeze

storage condition

-

storage condition

-

storage condition

-

color

white

color

-

color

-

color

-

solubility

water: 30 mg/mL

solubility

-

solubility

-

solubility

-

General description

A widely used anti-neoplastic agent that also displays immunosuppressant properties. Induces apoptotic cell death in rat thymus through the Fas/Fas ligand pathway.
A widely used antineoplastic agent that also displays immuno-suppressant activity. Induces apoptotic cell death in rat thymus throught Fas/Fas ligand pathway.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Fas/Fas ligand pathway
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

Reconstitution

Solutions should be prepared fresh on the day of use.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Wang, G.J., and Cai, L. 1999. Mutat. Res.427, 125.
Lee, J.H., et al. 1997. Korean J. Med. Sci. 12, 185.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3


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